Basic Information
ID: ALA5050894
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 20 mins in presence of NADPH and measured by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA5050894
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.33 | 5.47 | 5.47 |
| 495.38 | 5.83 | 5.83 |
| 509.41 | 6.14 | 6.14 |
| 484.36 | 6.03 | 6.03 |
| 513.43 | 5.09 | 5.09 |
| 482.34 | 4.67 | 4.67 |
| 509.41 | 6.14 | 6.14 |
| 511.45 | 6.30 | 6.30 |
| 484.36 | 5.78 | 5.78 |
| 481.36 | 5.27 | 5.27 |
| 495.38 | 5.83 | 5.83 |
| 526.47 | 6.00 | 6.00 |
| 495.39 | 4.76 | 4.76 |
| 496.37 | 5.23 | 5.23 |
| 482.34 | 4.67 | 4.67 |
| 512.44 | 5.70 | 5.70 |
| 513.43 | 5.09 | 5.09 |