Assay Report Card

Basic Information

ID: ALA5051111

Type: Binding

Description: Induction of IKZF2 degradation in human GripTite 293 MSR cells assessed as reduction in IKZF2 level measured by PathHunter assay

Organism: Homo sapiens

Cell type: GripTite 293 MSR

Activity Charts

Bioactivity

Activity Types for Assay ALA5051111

EC50

Total(170)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
449.53	3.34	3.34
483.57	3.01	3.01
531.58	2.82	2.82
447.54	2.43	2.43
355.44	1.65	1.65
545.68	2.28	2.28
453.49	3.11	3.11
524.64	2.08	2.08
471.60	3.71	3.71
457.53	2.70	2.70
469.49	2.81	2.81
395.50	2.43	2.43
480.63	3.58	3.58
462.55	2.14	2.14
401.47	2.35	2.35
447.54	2.32	2.32
434.50	1.20	1.20
504.59	1.45	1.45
489.57	2.99	2.99
461.52	2.53	2.53
493.61	4.49	4.49
460.53	1.93	1.93
483.57	3.01	3.01
425.53	2.05	2.05
442.52	2.70	2.70
530.67	3.44	3.44
475.55	2.45	2.45
553.50	4.86	4.86
435.53	2.04	2.04
447.54	2.84	2.84
449.51	1.63	1.63
472.55	2.73	2.73
476.58	3.01	3.01
417.51	2.83	2.83
422.49	2.12	2.12
468.56	3.38	3.38
452.47	0.31	0.31
531.53	3.93	3.93
453.49	3.11	3.11
471.56	2.71	2.71
488.55	1.88	1.88
467.52	3.76	3.76
445.56	3.44	3.44
421.50	1.56	1.56
423.44	2.58	2.58
431.54	3.14	3.14
459.59	3.78	3.78
458.52	1.87	1.87
467.52	3.63	3.63
460.53	1.93	1.93
457.53	2.70	2.70
431.54	3.07	3.07
468.56	3.38	3.38
442.52	2.70	2.70
431.54	3.22	3.22
443.51	2.09	2.09
407.47	1.55	1.55
501.51	3.73	3.73
433.51	1.80	1.80
519.64	4.12	4.12
451.95	3.48	3.48
469.55	2.77	2.77
473.53	2.00	2.00
418.50	2.22	2.22
451.95	3.48	3.48
470.57	3.62	3.62
445.56	3.44	3.44
325.37	0.82	0.82
447.54	2.36	2.36
477.59	2.84	2.84
484.56	2.61	2.61
407.47	1.55	1.55
475.59	3.61	3.61
458.97	2.94	2.94
456.55	3.31	3.31
431.54	3.39	3.39
456.55	2.89	2.89
487.64	4.51	4.51
453.49	3.11	3.11
483.57	3.01	3.01
486.55	3.51	3.51
431.54	3.14	3.14
474.56	2.79	2.79
453.49	3.11	3.11
423.56	3.21	3.21
431.54	3.39	3.39
485.51	3.85	3.85
497.50	3.15	3.15
476.58	3.01	3.01
491.66	4.33	4.33
458.52	1.87	1.87
457.53	2.70	2.70
474.59	3.44	3.44
449.53	3.30	3.30
483.57	3.22	3.22
431.54	2.87	2.87
477.56	3.22	3.22
431.54	3.14	3.14
491.57	2.13	2.13
483.57	3.22	3.22
566.68	1.85	1.85
498.58	3.79	3.79
524.64	2.08	2.08
461.52	2.53	2.53
461.57	2.36	2.36
458.52	1.87	1.87
431.54	3.22	3.22
445.56	3.39	3.39
489.57	3.36	3.36
471.60	3.75	3.75
483.52	3.43	3.43
466.49	1.60	1.60
383.49	2.28	2.28
421.50	1.56	1.56
442.52	2.70	2.70
409.41	2.19	2.19
473.62	4.12	4.12
415.49	2.74	2.74
408.46	1.82	1.82
431.54	3.39	3.39
483.52	3.43	3.43
449.53	3.27	3.27
409.45	1.21	1.21
418.50	2.22	2.22
475.55	2.60	2.60
467.57	3.98	3.98
475.55	2.60	2.60
485.51	3.85	3.85
419.49	1.62	1.62
486.49	3.24	3.24
461.56	3.23	3.23
501.51	3.73	3.73
468.56	3.38	3.38
424.53	2.28	2.28
485.63	4.48	4.48
436.52	1.14	1.14
564.71	5.41	5.41
453.49	3.11	3.11
447.54	2.36	2.36
381.48	2.04	2.04
449.56	2.60	2.60
493.56	2.84	2.84
457.53	2.70	2.70
481.52	2.97	2.97
459.59	3.95	3.95
457.57	3.70	3.70
406.49	2.16	2.16
499.57	2.14	2.14
507.54	2.88	2.88
467.57	3.98	3.98
451.95	3.48	3.48
474.59	3.44	3.44
461.56	2.97	2.97
487.60	3.76	3.76
541.62	4.55	4.55
486.40	4.13	4.13
445.56	3.46	3.46
490.63	3.34	3.34
449.51	2.44	2.44
407.47	1.55	1.55
471.60	3.71	3.71
435.53	1.87	1.87
457.53	2.47	2.47
424.53	2.28	2.28
483.52	3.43	3.43
524.62	3.80	3.80
488.59	2.22	2.22
484.56	2.61	2.61
500.62	3.95	3.95
467.52	3.76	3.76