Assay Report Card

Basic Information

ID: ALA5051112

Type: Binding

Description: Induction of IKZF2 degradation in human GripTite 293 MSR cells at 10 uM assessed as reduction in IKZF2 level measured by PathHunter assay relative to control

Organism: Homo sapiens

Cell type: GripTite 293 MSR

Activity Charts

Bioactivity

Activity Types for Assay ALA5051112

Activity

Total(177)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
449.53	3.34	3.34
483.57	3.01	3.01
531.58	2.82	2.82
447.54	2.43	2.43
355.44	1.65	1.65
545.68	2.28	2.28
453.49	3.11	3.11
524.64	2.08	2.08
471.60	3.71	3.71
457.53	2.70	2.70
469.49	2.81	2.81
395.50	2.43	2.43
480.63	3.58	3.58
462.55	2.14	2.14
401.47	2.35	2.35
447.54	2.32	2.32
434.50	1.20	1.20
504.59	1.45	1.45
339.40	1.17	1.17
489.57	2.99	2.99
461.52	2.53	2.53
493.61	4.49	4.49
460.53	1.93	1.93
483.57	3.01	3.01
425.53	2.05	2.05
442.52	2.70	2.70
530.67	3.44	3.44
475.55	2.45	2.45
553.50	4.86	4.86
435.53	2.04	2.04
447.54	2.84	2.84
449.51	1.63	1.63
472.55	2.73	2.73
476.58	3.01	3.01
417.51	2.83	2.83
341.41	1.30	1.30
399.45	0.80	0.80
422.49	2.12	2.12
341.41	1.30	1.30
468.56	3.38	3.38
452.47	0.31	0.31
531.53	3.93	3.93
453.49	3.11	3.11
363.85	0.91	0.91
403.48	2.48	2.48
471.56	2.71	2.71
488.55	1.88	1.88
467.52	3.76	3.76
445.56	3.44	3.44
421.50	1.56	1.56
423.44	2.58	2.58
431.54	3.14	3.14
459.59	3.78	3.78
458.52	1.87	1.87
467.52	3.63	3.63
460.53	1.93	1.93
457.53	2.70	2.70
431.54	3.07	3.07
468.56	3.38	3.38
442.52	2.70	2.70
431.54	3.22	3.22
443.51	2.09	2.09
407.47	1.55	1.55
501.51	3.73	3.73
433.51	1.80	1.80
519.64	4.12	4.12
451.95	3.48	3.48
469.55	2.77	2.77
473.53	2.00	2.00
418.50	2.22	2.22
451.95	3.48	3.48
470.57	3.62	3.62
445.56	3.44	3.44
325.37	0.82	0.82
447.54	2.36	2.36
477.59	2.84	2.84
484.56	2.61	2.61
407.47	1.55	1.55
475.59	3.61	3.61
458.97	2.94	2.94
456.55	3.31	3.31
431.54	3.39	3.39
456.55	2.89	2.89
487.64	4.51	4.51
453.49	3.11	3.11
483.57	3.01	3.01
486.55	3.51	3.51
431.54	3.14	3.14
474.56	2.79	2.79
453.49	3.11	3.11
423.56	3.21	3.21
431.54	3.39	3.39
485.51	3.85	3.85
497.50	3.15	3.15
476.58	3.01	3.01
491.66	4.33	4.33
458.52	1.87	1.87
457.53	2.70	2.70
474.59	3.44	3.44
449.53	3.30	3.30
483.57	3.22	3.22
431.54	2.87	2.87
477.56	3.22	3.22
431.54	3.14	3.14
491.57	2.13	2.13
483.57	3.22	3.22
566.68	1.85	1.85
498.58	3.79	3.79
524.64	2.08	2.08
461.52	2.53	2.53
461.57	2.36	2.36
458.52	1.87	1.87
431.54	3.22	3.22
445.56	3.39	3.39
489.57	3.36	3.36
471.60	3.75	3.75
483.52	3.43	3.43
466.49	1.60	1.60
383.49	2.28	2.28
421.50	1.56	1.56
442.52	2.70	2.70
409.41	2.19	2.19
473.62	4.12	4.12
415.49	2.74	2.74
408.46	1.82	1.82
431.54	3.39	3.39
483.52	3.43	3.43
449.53	3.27	3.27
409.45	1.21	1.21
418.50	2.22	2.22
475.55	2.60	2.60
467.57	3.98	3.98
475.55	2.60	2.60
485.51	3.85	3.85
419.49	1.62	1.62
486.49	3.24	3.24
461.56	3.23	3.23
501.51	3.73	3.73
468.56	3.38	3.38
441.53	1.97	1.97
424.53	2.28	2.28
485.63	4.48	4.48
436.52	1.14	1.14
564.71	5.41	5.41
453.49	3.11	3.11
447.54	2.36	2.36
381.48	2.04	2.04
449.56	2.60	2.60
493.56	2.84	2.84
457.53	2.70	2.70
481.52	2.97	2.97
459.59	3.95	3.95
457.57	3.70	3.70
406.49	2.16	2.16
499.57	2.14	2.14
507.54	2.88	2.88
467.57	3.98	3.98
451.95	3.48	3.48
474.59	3.44	3.44
461.56	2.97	2.97
487.60	3.76	3.76
541.62	4.55	4.55
486.40	4.13	4.13
445.56	3.46	3.46
490.63	3.34	3.34
449.51	2.44	2.44
407.47	1.55	1.55
471.60	3.71	3.71
435.53	1.87	1.87
457.53	2.47	2.47
424.53	2.28	2.28
483.52	3.43	3.43
524.62	3.80	3.80
488.59	2.22	2.22
484.56	2.61	2.61
500.62	3.95	3.95
467.52	3.76	3.76