Assay Report Card

Basic Information

ID: ALA5051113

Type: Binding

Description: Induction of IKZF1 degradation in human GripTite 293 MSR cells assessed as reduction in IKZF1 level measured by PathHunter assay

Organism: Homo sapiens

Cell type: GripTite 293 MSR

Activity Charts

Bioactivity

Activity Types for Assay ALA5051113

EC50

Total(177)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
449.53	3.34	3.34
483.57	3.01	3.01
531.58	2.82	2.82
447.54	2.43	2.43
355.44	1.65	1.65
545.68	2.28	2.28
453.49	3.11	3.11
524.64	2.08	2.08
471.60	3.71	3.71
457.53	2.70	2.70
469.49	2.81	2.81
395.50	2.43	2.43
480.63	3.58	3.58
462.55	2.14	2.14
401.47	2.35	2.35
447.54	2.32	2.32
434.50	1.20	1.20
504.59	1.45	1.45
339.40	1.17	1.17
489.57	2.99	2.99
461.52	2.53	2.53
493.61	4.49	4.49
460.53	1.93	1.93
483.57	3.01	3.01
425.53	2.05	2.05
442.52	2.70	2.70
530.67	3.44	3.44
475.55	2.45	2.45
553.50	4.86	4.86
435.53	2.04	2.04
447.54	2.84	2.84
449.51	1.63	1.63
472.55	2.73	2.73
476.58	3.01	3.01
417.51	2.83	2.83
341.41	1.30	1.30
399.45	0.80	0.80
422.49	2.12	2.12
341.41	1.30	1.30
468.56	3.38	3.38
452.47	0.31	0.31
531.53	3.93	3.93
453.49	3.11	3.11
363.85	0.91	0.91
403.48	2.48	2.48
471.56	2.71	2.71
488.55	1.88	1.88
467.52	3.76	3.76
445.56	3.44	3.44
421.50	1.56	1.56
423.44	2.58	2.58
431.54	3.14	3.14
459.59	3.78	3.78
458.52	1.87	1.87
467.52	3.63	3.63
460.53	1.93	1.93
457.53	2.70	2.70
431.54	3.07	3.07
468.56	3.38	3.38
442.52	2.70	2.70
431.54	3.22	3.22
443.51	2.09	2.09
407.47	1.55	1.55
501.51	3.73	3.73
433.51	1.80	1.80
519.64	4.12	4.12
451.95	3.48	3.48
469.55	2.77	2.77
473.53	2.00	2.00
418.50	2.22	2.22
451.95	3.48	3.48
470.57	3.62	3.62
445.56	3.44	3.44
325.37	0.82	0.82
447.54	2.36	2.36
477.59	2.84	2.84
484.56	2.61	2.61
407.47	1.55	1.55
475.59	3.61	3.61
458.97	2.94	2.94
456.55	3.31	3.31
431.54	3.39	3.39
456.55	2.89	2.89
487.64	4.51	4.51
453.49	3.11	3.11
483.57	3.01	3.01
486.55	3.51	3.51
431.54	3.14	3.14
474.56	2.79	2.79
453.49	3.11	3.11
423.56	3.21	3.21
431.54	3.39	3.39
485.51	3.85	3.85
497.50	3.15	3.15
476.58	3.01	3.01
491.66	4.33	4.33
458.52	1.87	1.87
457.53	2.70	2.70
474.59	3.44	3.44
449.53	3.30	3.30
483.57	3.22	3.22
431.54	2.87	2.87
477.56	3.22	3.22
431.54	3.14	3.14
491.57	2.13	2.13
483.57	3.22	3.22
566.68	1.85	1.85
498.58	3.79	3.79
524.64	2.08	2.08
461.52	2.53	2.53
461.57	2.36	2.36
458.52	1.87	1.87
431.54	3.22	3.22
445.56	3.39	3.39
489.57	3.36	3.36
471.60	3.75	3.75
483.52	3.43	3.43
466.49	1.60	1.60
383.49	2.28	2.28
421.50	1.56	1.56
442.52	2.70	2.70
409.41	2.19	2.19
473.62	4.12	4.12
415.49	2.74	2.74
408.46	1.82	1.82
431.54	3.39	3.39
483.52	3.43	3.43
449.53	3.27	3.27
409.45	1.21	1.21
418.50	2.22	2.22
475.55	2.60	2.60
467.57	3.98	3.98
475.55	2.60	2.60
485.51	3.85	3.85
419.49	1.62	1.62
486.49	3.24	3.24
461.56	3.23	3.23
501.51	3.73	3.73
468.56	3.38	3.38
441.53	1.97	1.97
424.53	2.28	2.28
485.63	4.48	4.48
436.52	1.14	1.14
564.71	5.41	5.41
453.49	3.11	3.11
447.54	2.36	2.36
381.48	2.04	2.04
449.56	2.60	2.60
493.56	2.84	2.84
457.53	2.70	2.70
481.52	2.97	2.97
459.59	3.95	3.95
457.57	3.70	3.70
406.49	2.16	2.16
499.57	2.14	2.14
507.54	2.88	2.88
467.57	3.98	3.98
451.95	3.48	3.48
474.59	3.44	3.44
461.56	2.97	2.97
487.60	3.76	3.76
541.62	4.55	4.55
486.40	4.13	4.13
445.56	3.46	3.46
490.63	3.34	3.34
449.51	2.44	2.44
407.47	1.55	1.55
471.60	3.71	3.71
435.53	1.87	1.87
457.53	2.47	2.47
424.53	2.28	2.28
483.52	3.43	3.43
524.62	3.80	3.80
488.59	2.22	2.22
484.56	2.61	2.61
500.62	3.95	3.95
467.52	3.76	3.76