Positive allosteric modulation of recombinant N-terminal poly-His tagged rat neurolysin using Mca-Pro-Leu- Gly-Pro-D-Lys(DNP)-OH as substrate assessed...

Basic Information

ID: ALA5051247

Type: Binding

Description: Positive allosteric modulation of recombinant N-terminal poly-His tagged rat neurolysin using Mca-Pro-Leu- Gly-Pro-D-Lys(DNP)-OH as substrate assessed as Amax and measured by fluorescence based assay relative to control

Format: BAO_0000019

Organism: Rattus norvegicus

Target: Unchecked(ALA612545)

Document: ALA5050845

Positive allosteric modulation of recombinant N-terminal poly-His tagged rat neurolysin using Mca-Pro-Leu- Gly-Pro-D-Lys(DNP)-OH as substrate assessed as Amax and measured by fluorescence based assay relative to control: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5051247

Emax

Total(44)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
208.26	-0.10	-0.10
302.33	0.09	0.09
318.33	-0.20	-0.20
297.36	1.12	1.12
288.35	0.65	0.65
274.32	0.60	0.60
312.30	1.61	1.61
294.36	1.75	1.75
244.30	0.60	0.60
276.31	0.78	0.78
234.26	-0.56	-0.56
258.32	0.64	0.64
397.48	2.69	2.69
341.37	0.57	0.57
282.35	2.18	2.18
288.35	0.65	0.65
297.36	1.12	1.12
288.35	0.65	0.65
312.30	1.61	1.61
326.32	1.66	1.66
262.29	0.73	0.73
326.32	1.66	1.66
294.36	1.75	1.75
397.48	2.69	2.69
405.50	1.37	1.37
274.32	0.60	0.60
312.30	1.61	1.61
269.35	1.31	1.31
312.30	1.61	1.61
402.45	1.66	1.66
297.36	1.12	1.12
288.35	0.65	0.65
238.25	-0.51	-0.51
258.32	0.64	0.64
312.30	1.61	1.61
358.44	2.20	2.20
326.32	1.66	1.66
274.32	0.60	0.60
294.36	1.75	1.75
274.32	0.60	0.60
288.35	0.65	0.65
230.27	0.92	0.92
308.38	1.79	1.79
308.38	1.79	1.79