Basic Information
ID: ALA5051733
Type: Binding
Description: Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5051733
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 586.71 | 5.03 | 5.03 |
| 600.74 | 5.34 | 5.34 |
| 587.70 | 4.43 | 4.43 |
| 463.58 | 6.30 | 6.30 |
| 587.70 | 4.43 | 4.43 |
| 566.72 | 6.87 | 6.87 |
| 579.65 | 5.13 | 5.13 |
| 588.69 | 3.82 | 3.82 |
| 541.67 | 5.70 | 5.70 |
| 587.69 | 5.08 | 5.08 |
| 481.62 | 4.10 | 4.10 |
| 586.71 | 5.03 | 5.03 |
| 566.72 | 6.87 | 6.87 |
| 565.62 | 4.82 | 4.82 |