Assay Report Card

Basic Information

ID: ALA5051763

Type: Binding

Description: Inhibition of METTL1 (unknown origin) using GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUG GUUCAAUCCCGGGUUUCGGCA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 20 mins by TopCount scintillation counting method

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA5051763

IC50

Total(143)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
389.46	2.48	2.48
404.47	2.06	2.06
458.57	3.30	3.30
504.59	3.35	3.35
502.54	1.70	1.70
504.52	3.85	3.85
448.53	2.01	2.01
460.54	2.41	2.41
518.55	2.78	2.78
540.57	3.59	3.59
476.54	2.39	2.39
483.37	2.82	2.82
500.65	4.57	4.57
456.89	1.96	1.96
404.47	2.06	2.06
504.59	3.03	3.03
355.40	0.62	0.62
474.57	3.99	3.99
508.63	4.13	4.13
394.44	1.10	1.10
389.46	2.48	2.48
404.47	2.06	2.06
440.89	2.98	2.98
388.47	3.08	3.08
460.54	2.52	2.52
423.43	0.70	0.70
542.60	2.89	2.89
420.47	1.81	1.81
390.45	1.87	1.87
408.42	0.84	0.84
464.50	3.16	3.16
432.53	2.54	2.54
422.45	1.15	1.15
339.40	1.32	1.32
458.57	3.08	3.08
432.53	2.83	2.83
406.45	1.51	1.51
487.31	1.60	1.60
446.56	3.30	3.30
501.52	3.34	3.34
446.56	3.30	3.30
377.45	2.41	2.41
442.43	2.42	2.42
438.46	2.59	2.59
532.58	3.24	3.24
436.47	1.61	1.61
488.59	3.51	3.51
432.53	2.83	2.83
446.56	3.01	3.01
418.50	2.37	2.37
474.57	3.99	3.99
458.88	2.93	2.93
396.45	1.42	1.42
492.43	3.30	3.30
378.44	1.81	1.81
521.60	3.09	3.09
494.53	3.26	3.26
436.47	1.61	1.61
418.50	2.37	2.37
485.34	2.94	2.94
436.49	2.66	2.66
436.47	1.33	1.33
406.45	1.40	1.40
462.51	2.03	2.03
491.53	2.27	2.27
512.57	2.91	2.91
485.34	3.09	3.09
508.63	4.13	4.13
369.43	1.33	1.33
489.58	3.88	3.88
530.56	2.85	2.85
482.59	3.88	3.88
494.60	4.09	4.09
554.38	3.40	3.40
390.45	1.87	1.87
378.44	1.81	1.81
478.53	3.23	3.23
492.56	3.94	3.94
448.53	1.88	1.88
468.36	3.24	3.24
408.42	0.84	0.84
403.49	2.66	2.66
495.58	4.06	4.06
536.51	4.22	4.22
502.62	3.41	3.41
532.58	3.72	3.72
501.52	3.34	3.34
501.34	2.06	2.06
395.49	2.54	2.54
472.59	3.72	3.72
410.48	1.68	1.68
522.65	4.44	4.44
421.50	2.28	2.28
518.55	2.99	2.99
419.49	1.56	1.56
418.50	2.37	2.37
490.56	2.96	2.96
476.54	2.25	2.25
480.57	4.22	4.22
504.53	2.68	2.68
405.46	1.54	1.54
474.57	2.56	2.56
378.44	1.81	1.81
446.56	3.30	3.30
390.45	1.87	1.87
515.55	3.65	3.65
418.50	2.37	2.37
436.47	1.69	1.69
418.50	2.52	2.52
480.34	2.51	2.51
339.40	1.32	1.32
503.33	3.04	3.04
403.49	2.66	2.66
462.51	1.86	1.86
418.50	2.52	2.52
474.57	2.56	2.56
518.35	2.62	2.62
424.44	2.28	2.28
472.91	3.32	3.32
472.59	4.65	4.65
418.50	2.52	2.52
504.59	2.98	2.98
502.34	3.65	3.65
503.32	0.85	0.85
482.47	2.07	2.07
459.55	3.27	3.27
510.60	3.58	3.58
504.59	3.35	3.35
478.28	1.91	1.91
515.55	3.65	3.65
500.65	4.57	4.57
478.51	1.10	1.10
377.45	2.41	2.41
492.54	1.74	1.74
390.45	1.87	1.87
490.50	2.67	2.67
519.58	3.00	3.00
392.46	1.89	1.89
546.56	2.71	2.71
486.62	4.18	4.18
541.41	2.62	2.62
518.55	3.07	3.07
484.56	2.46	2.46