Basic Information
ID: ALA5051763
Type: Binding
Description: Inhibition of METTL1 (unknown origin) using GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUG GUUCAAUCCCGGGUUUCGGCA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 20 mins by TopCount scintillation counting method
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA5050857
Inhibition of METTL1 (unknown origin) using GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUG GUUCAAUCCCGGGUUUCGGCA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 20 mins by TopCount scintillation counting method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA5051763
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.59 | 3.35 | 3.35 |
| 502.54 | 1.70 | 1.70 |
| 448.53 | 2.01 | 2.01 |
| 460.54 | 2.41 | 2.41 |
| 540.57 | 3.59 | 3.59 |
| 476.54 | 2.39 | 2.39 |
| 483.37 | 2.82 | 2.82 |
| 500.65 | 4.57 | 4.57 |
| 456.89 | 1.96 | 1.96 |
| 504.59 | 3.03 | 3.03 |
| 355.40 | 0.62 | 0.62 |
| 474.57 | 3.99 | 3.99 |
| 508.63 | 4.13 | 4.13 |
| 394.44 | 1.10 | 1.10 |
| 404.47 | 2.06 | 2.06 |
| 440.89 | 2.98 | 2.98 |
| 460.54 | 2.52 | 2.52 |
| 423.43 | 0.70 | 0.70 |
| 420.47 | 1.81 | 1.81 |
| 408.42 | 0.84 | 0.84 |
| 464.50 | 3.16 | 3.16 |
| 432.53 | 2.54 | 2.54 |
| 422.45 | 1.15 | 1.15 |
| 458.57 | 3.08 | 3.08 |
| 432.53 | 2.83 | 2.83 |
| 487.31 | 1.60 | 1.60 |
| 446.56 | 3.30 | 3.30 |
| 501.52 | 3.34 | 3.34 |
| 377.45 | 2.41 | 2.41 |
| 438.46 | 2.59 | 2.59 |
| 436.47 | 1.61 | 1.61 |
| 488.59 | 3.51 | 3.51 |
| 432.53 | 2.83 | 2.83 |
| 446.56 | 3.01 | 3.01 |
| 418.50 | 2.37 | 2.37 |
| 458.88 | 2.93 | 2.93 |
| 396.45 | 1.42 | 1.42 |
| 492.43 | 3.30 | 3.30 |
| 378.44 | 1.81 | 1.81 |
| 521.60 | 3.09 | 3.09 |
| 436.47 | 1.61 | 1.61 |
| 418.50 | 2.37 | 2.37 |
| 485.34 | 2.94 | 2.94 |
| 436.49 | 2.66 | 2.66 |
| 436.47 | 1.33 | 1.33 |
| 491.53 | 2.27 | 2.27 |
| 485.34 | 3.09 | 3.09 |
| 369.43 | 1.33 | 1.33 |
| 489.58 | 3.88 | 3.88 |
| 482.59 | 3.88 | 3.88 |
| 554.38 | 3.40 | 3.40 |
| 378.44 | 1.81 | 1.81 |
| 478.53 | 3.23 | 3.23 |
| 492.56 | 3.94 | 3.94 |
| 448.53 | 1.88 | 1.88 |
| 408.42 | 0.84 | 0.84 |
| 403.49 | 2.66 | 2.66 |
| 495.58 | 4.06 | 4.06 |
| 536.51 | 4.22 | 4.22 |
| 502.62 | 3.41 | 3.41 |
| 501.52 | 3.34 | 3.34 |
| 501.34 | 2.06 | 2.06 |
| 395.49 | 2.54 | 2.54 |
| 472.59 | 3.72 | 3.72 |
| 410.48 | 1.68 | 1.68 |
| 522.65 | 4.44 | 4.44 |
| 421.50 | 2.28 | 2.28 |
| 419.49 | 1.56 | 1.56 |
| 490.56 | 2.96 | 2.96 |
| 504.53 | 2.68 | 2.68 |
| 405.46 | 1.54 | 1.54 |
| 474.57 | 2.56 | 2.56 |
| 378.44 | 1.81 | 1.81 |
| 418.50 | 2.37 | 2.37 |
| 436.47 | 1.69 | 1.69 |
| 480.34 | 2.51 | 2.51 |
| 503.33 | 3.04 | 3.04 |
| 403.49 | 2.66 | 2.66 |
| 462.51 | 1.86 | 1.86 |
| 474.57 | 2.56 | 2.56 |
| 518.35 | 2.62 | 2.62 |
| 424.44 | 2.28 | 2.28 |
| 472.59 | 4.65 | 4.65 |
| 418.50 | 2.52 | 2.52 |
| 504.59 | 2.98 | 2.98 |
| 502.34 | 3.65 | 3.65 |
| 503.32 | 0.85 | 0.85 |
| 459.55 | 3.27 | 3.27 |
| 510.60 | 3.58 | 3.58 |
| 504.59 | 3.35 | 3.35 |
| 478.28 | 1.91 | 1.91 |
| 500.65 | 4.57 | 4.57 |
| 478.51 | 1.10 | 1.10 |
| 377.45 | 2.41 | 2.41 |
| 519.58 | 3.00 | 3.00 |
| 392.46 | 1.89 | 1.89 |
| 486.62 | 4.18 | 4.18 |
| 541.41 | 2.62 | 2.62 |
| 518.55 | 3.07 | 3.07 |
| 484.56 | 2.46 | 2.46 |