Basic Information
ID: ALA5051765
Type: Binding
Description: Inhibition of METTL3-mediated m6A methylation in human MOLM-13 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MOLM-13
Target: N6-adenosine-methyltransferase catalytic subunit(ALA4739695)
Document: ALA5050857
Inhibition of METTL3-mediated m6A methylation in human MOLM-13 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA5051765
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.59 | 3.35 | 3.35 |
| 520.57 | 3.30 | 3.30 |
| 502.54 | 1.70 | 1.70 |
| 531.55 | 3.41 | 3.41 |
| 516.54 | 2.63 | 2.63 |
| 504.52 | 3.85 | 3.85 |
| 448.53 | 2.01 | 2.01 |
| 500.65 | 4.57 | 4.57 |
| 456.89 | 1.96 | 1.96 |
| 504.59 | 3.03 | 3.03 |
| 474.57 | 3.99 | 3.99 |
| 491.48 | 2.93 | 2.93 |
| 520.57 | 3.30 | 3.30 |
| 440.89 | 2.98 | 2.98 |
| 530.56 | 2.94 | 2.94 |
| 464.50 | 3.16 | 3.16 |
| 432.53 | 2.54 | 2.54 |
| 339.40 | 1.32 | 1.32 |
| 494.53 | 3.13 | 3.13 |
| 501.52 | 3.34 | 3.34 |
| 510.60 | 3.56 | 3.56 |
| 546.56 | 1.82 | 1.82 |
| 532.58 | 3.24 | 3.24 |
| 488.59 | 3.51 | 3.51 |
| 432.53 | 2.83 | 2.83 |
| 458.88 | 2.93 | 2.93 |
| 436.47 | 1.33 | 1.33 |
| 530.56 | 2.85 | 2.85 |
| 478.53 | 3.23 | 3.23 |
| 492.56 | 3.94 | 3.94 |
| 498.55 | 2.68 | 2.68 |
| 494.53 | 3.13 | 3.13 |
| 512.57 | 3.26 | 3.26 |
| 501.34 | 2.06 | 2.06 |
| 508.63 | 4.12 | 4.12 |
| 490.56 | 2.96 | 2.96 |
| 503.33 | 3.04 | 3.04 |
| 462.51 | 1.86 | 1.86 |
| 424.44 | 2.28 | 2.28 |
| 472.91 | 3.32 | 3.32 |
| 512.57 | 2.90 | 2.90 |
| 504.59 | 2.98 | 2.98 |
| 504.59 | 3.35 | 3.35 |
| 500.65 | 4.57 | 4.57 |
| 504.53 | 2.68 | 2.68 |
| 490.50 | 2.67 | 2.67 |
| 544.59 | 3.60 | 3.60 |
| 486.62 | 4.18 | 4.18 |
| 518.55 | 3.07 | 3.07 |
| 504.53 | 2.68 | 2.68 |