Basic Information
ID: ALA5051783
Type: ADME
Description: Stability of compound in rat microsomes assessed as half-life
Organism: Rattus norvegicus
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5051783
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.92 | 3.09 | 3.09 |
| 409.48 | 3.28 | 3.28 |
| 510.38 | 4.47 | 4.47 |
| 557.05 | 5.34 | 5.34 |
| 488.94 | 4.39 | 4.39 |
| 532.94 | 4.61 | 4.61 |
| 529.98 | 4.97 | 4.97 |
| 479.95 | 4.67 | 4.67 |
| 502.92 | 4.60 | 4.60 |
| 501.97 | 4.68 | 4.68 |
| 565.91 | 4.65 | 4.65 |
| 521.98 | 4.85 | 4.85 |
| 586.97 | 4.92 | 4.92 |
| 502.92 | 4.60 | 4.60 |
| 494.96 | 4.46 | 4.46 |
| 577.46 | 6.07 | 6.07 |
| 493.98 | 4.99 | 4.99 |
| 501.97 | 5.19 | 5.19 |
| 492.37 | 6.16 | 6.16 |
| 537.00 | 4.43 | 4.43 |
| 590.01 | 5.34 | 5.34 |
| 438.92 | 5.07 | 5.07 |
| 475.94 | 3.92 | 3.92 |
| 560.95 | 4.40 | 4.40 |
| 561.00 | 5.56 | 5.56 |
| 502.92 | 5.41 | 5.41 |
| 571.04 | 4.98 | 4.98 |
| 452.95 | 3.55 | 3.55 |
| 493.95 | 3.59 | 3.59 |
| 532.94 | 4.61 | 4.61 |
| 508.01 | 5.38 | 5.38 |
| 499.48 | 4.72 | 4.72 |
| 516.95 | 4.69 | 4.69 |
| 516.95 | 4.69 | 4.69 |
| 504.98 | 3.81 | 3.81 |
| 519.92 | 4.14 | 4.14 |
| 504.98 | 3.26 | 3.26 |
| 463.93 | 3.92 | 3.92 |
| 519.92 | 5.34 | 5.34 |
| 502.92 | 4.60 | 4.60 |
| 487.95 | 5.00 | 5.00 |
| 416.89 | 3.87 | 3.87 |
| 473.92 | 4.48 | 4.48 |
| 542.98 | 5.42 | 5.42 |
| 522.97 | 4.75 | 4.75 |
| 502.92 | 4.60 | 4.60 |
| 588.91 | 5.76 | 5.76 |
| 501.93 | 5.20 | 5.20 |
| 524.97 | 5.29 | 5.29 |
| 519.97 | 4.32 | 4.32 |
| 519.01 | 4.29 | 4.29 |
| 517.93 | 4.18 | 4.18 |
| 486.96 | 4.97 | 4.97 |
| 501.91 | 4.91 | 4.91 |
| 490.96 | 3.62 | 3.62 |
| 492.37 | 6.16 | 6.16 |
| 475.94 | 3.92 | 3.92 |
| 494.96 | 4.46 | 4.46 |
| 547.96 | 4.19 | 4.19 |
| 493.91 | 3.03 | 3.03 |
| 449.90 | 3.57 | 3.57 |
| 516.95 | 4.69 | 4.69 |
| 531.96 | 4.49 | 4.49 |
| 536.82 | 6.27 | 6.27 |
| 506.39 | 5.84 | 5.84 |
| 542.04 | 4.92 | 4.92 |
| 584.06 | 5.88 | 5.88 |
| 534.94 | 5.05 | 5.05 |
| 502.92 | 4.60 | 4.60 |
| 514.37 | 3.20 | 3.20 |
| 604.04 | 5.73 | 5.73 |
| 539.43 | 4.64 | 4.64 |
| 543.01 | 5.42 | 5.42 |
| 523.98 | 5.90 | 5.90 |
| 520.91 | 4.74 | 4.74 |
| 526.00 | 5.07 | 5.07 |
| 536.01 | 4.98 | 4.98 |
| 523.98 | 5.90 | 5.90 |
| 455.89 | 3.08 | 3.08 |
| 493.35 | 5.55 | 5.55 |
| 519.90 | 4.90 | 4.90 |
| 490.96 | 3.62 | 3.62 |
| 501.93 | 5.20 | 5.20 |
| 393.83 | 3.37 | 3.37 |
| 569.02 | 4.88 | 4.88 |
| 557.42 | 4.78 | 4.78 |
| 525.40 | 4.15 | 4.15 |
| 543.39 | 4.29 | 4.29 |
| 500.95 | 4.61 | 4.61 |
| 508.95 | 3.64 | 3.64 |
| 607.03 | 6.15 | 6.15 |
| 511.37 | 3.86 | 3.86 |
| 581.08 | 5.32 | 5.32 |
| 515.96 | 4.88 | 4.88 |
| 529.97 | 4.29 | 4.29 |
| 612.02 | 6.11 | 6.11 |
| 538.90 | 4.88 | 4.88 |
| 457.92 | 5.51 | 5.51 |
| 520.98 | 4.63 | 4.63 |
| 574.98 | 5.47 | 5.47 |
| 516.95 | 4.69 | 4.69 |
| 490.96 | 3.62 | 3.62 |
| 564.96 | 5.14 | 5.14 |
| 534.74 | ||
| 522.97 | 4.12 | 4.12 |
| 515.96 | 4.26 | 4.26 |
| 545.92 | 4.61 | 4.61 |
| 521.98 | 4.67 | 4.67 |
| 570.92 | 5.62 | 5.62 |
| 495.95 | 3.98 | 3.98 |
| 529.98 | 4.97 | 4.97 |
| 465.93 | 4.36 | 4.36 |
| 520.91 | 4.74 | 4.74 |
| 534.94 | 5.05 | 5.05 |
| 500.37 | 5.01 | 5.01 |
| 555.35 | 5.39 | 5.39 |
| 458.91 | 4.90 | 4.90 |
| 561.00 | 5.56 | 5.56 |
| 506.93 | 4.53 | 4.53 |
| 501.97 | 5.04 | 5.04 |
| 529.98 | 5.68 | 5.68 |
| 525.96 | 4.69 | 4.69 |
| 472.94 | 4.58 | 4.58 |
| 588.91 | 5.76 | 5.76 |
| 441.54 | 3.23 | 3.23 |
| 501.91 | 4.91 | 4.91 |
| 565.05 | 5.17 | 5.17 |
| 450.80 | 4.58 | 4.58 |
| 506.39 | 5.84 | 5.84 |
| 479.95 | 4.67 | 4.67 |
| 537.00 | 4.43 | 4.43 |
| 475.91 | 5.65 | 5.65 |
| 517.93 | 4.30 | 4.30 |
| 537.99 | 4.07 | 4.07 |
| 573.04 | 5.43 | 5.43 |
| 529.98 | 5.22 | 5.22 |
| 537.91 | 5.48 | 5.48 |
| 517.93 | 4.18 | 4.18 |
| 532.94 | 4.61 | 4.61 |
| 529.98 | 5.22 | 5.22 |
| 543.01 | 5.42 | 5.42 |
| 516.95 | 4.91 | 4.91 |
| 586.97 | 4.92 | 4.92 |
| 517.93 | 4.30 | 4.30 |
| 492.37 | 6.16 | 6.16 |
| 577.46 | 6.07 | 6.07 |
| 537.36 | 5.25 | 5.25 |
| 606.01 | 4.58 | 4.58 |
| 487.95 | 4.89 | 4.89 |
| 520.91 | 4.74 | 4.74 |
| 493.93 | 4.06 | 4.06 |
| 500.95 | 4.61 | 4.61 |
| 514.37 | 3.20 | 3.20 |
| 564.92 | 4.44 | 4.44 |
| 533.92 | 5.38 | 5.38 |
| 522.97 | 4.12 | 4.12 |
| 536.82 | 6.27 | 6.27 |
| 473.92 | 5.21 | 5.21 |
| 466.91 | 3.75 | 3.75 |
| 520.91 | 4.74 | 4.74 |
| 547.96 | 4.19 | 4.19 |
| 529.03 | 6.42 | 6.42 |
| 523.96 | 4.14 | 4.14 |
| 531.96 | 4.49 | 4.49 |
| 538.90 | 4.88 | 4.88 |
| 504.98 | 3.81 | 3.81 |
| 547.92 | 4.51 | 4.51 |
| 520.91 | 4.74 | 4.74 |
| 436.86 | 3.91 | 3.91 |
| 476.90 | 5.04 | 5.04 |
| 545.99 | 4.58 | 4.58 |
| 534.00 | 5.41 | 5.41 |
| 565.54 | 2.73 | 2.73 |
| 557.04 | 5.73 | 5.73 |
| 479.92 | 2.94 | 2.94 |
| 446.83 | 5.31 | 5.31 |
| 537.36 | 5.25 | 5.25 |
| 516.95 | 4.69 | 4.69 |
| 488.94 | 4.39 | 4.39 |
| 550.93 | 4.75 | 4.75 |
| 522.97 | 3.95 | 3.95 |
| 537.99 | 4.53 | 4.53 |
| 554.37 | 6.00 | 6.00 |
| 495.95 | 4.37 | 4.37 |
| 555.35 | 5.39 | 5.39 |
| 554.46 | 5.10 | 5.10 |
| 544.94 | 4.22 | 4.22 |
| 533.04 | 4.42 | 4.42 |
| 517.93 | 4.30 | 4.30 |
| 475.94 | 3.92 | 3.92 |
| 613.01 | 5.50 | 5.50 |
| 478.97 | 4.64 | 4.64 |
| 500.34 | 3.19 | 3.19 |
| 475.91 | 5.65 | 5.65 |
| 529.98 | 4.97 | 4.97 |
| 511.37 | 3.86 | 3.86 |
| 553.45 | 5.20 | 5.20 |
| 516.95 | 4.69 | 4.69 |
| 558.97 | 4.53 | 4.53 |
| 515.96 | 4.88 | 4.88 |
| 534.94 | 5.05 | 5.05 |
| 547.96 | 4.19 | 4.19 |
| 443.49 | 3.41 | 3.41 |
| 523.98 | 5.69 | 5.69 |
| 665.00 | 7.42 | 7.42 |
| 473.92 | 5.21 | 5.21 |
| 471.95 | 5.53 | 5.53 |
| 486.96 | 4.97 | 4.97 |
| 515.96 | 5.29 | 5.29 |
| 508.95 | 4.66 | 4.66 |
| 516.95 | 4.91 | 4.91 |
| 504.98 | 3.81 | 3.81 |
| 557.04 | 5.73 | 5.73 |
| 490.96 | 3.50 | 3.50 |
| 529.49 | 3.18 | 3.18 |
| 501.93 | 4.00 | 4.00 |
| 558.03 | 5.00 | 5.00 |
| 482.93 | 5.38 | 5.38 |
| 516.95 | 4.91 | 4.91 |
| 411.45 | 2.12 | 2.12 |
| 516.95 | 4.69 | 4.69 |
| 565.36 | 4.85 | 4.85 |
| 573.04 | 5.43 | 5.43 |
| 458.91 | 4.90 | 4.90 |
| 475.94 | 3.92 | 3.92 |
| 551.97 | 4.06 | 4.06 |
| 451.91 | 3.73 | 3.73 |
| 554.99 | 4.57 | 4.57 |
| 520.91 | 4.74 | 4.74 |
| 535.92 | 4.32 | 4.32 |
| 502.92 | 4.60 | 4.60 |
| 487.95 | 5.00 | 5.00 |
| 537.36 | 5.25 | 5.25 |
| 534.94 | 4.83 | 4.83 |
| 665.99 | 6.82 | 6.82 |
| 520.91 | 4.74 | 4.74 |
| 533.04 | 4.85 | 4.85 |
| 531.96 | 4.49 | 4.49 |
| 537.36 | 5.25 | 5.25 |
| 500.37 | 5.01 | 5.01 |
| 549.95 | 5.35 | 5.35 |
| 489.94 | 5.32 | 5.32 |
| 410.86 | 4.43 | 4.43 |
| 586.91 | 5.50 | 5.50 |
| 500.99 | 5.57 | 5.57 |
| 407.86 | 4.86 | 4.86 |
| 501.97 | 4.68 | 4.68 |
| 517.93 | 4.18 | 4.18 |
| 475.94 | 3.92 | 3.92 |
| 475.91 | 5.65 | 5.65 |
| 445.51 | 4.01 | 4.01 |
| 501.97 | 4.68 | 4.68 |
| 534.94 | 4.83 | 4.83 |
| 531.02 | 4.86 | 4.86 |
| 472.94 | 4.58 | 4.58 |
| 517.93 | 4.18 | 4.18 |
| 511.37 | 3.86 | 3.86 |
| 506.93 | 4.53 | 4.53 |
| 487.95 | 5.00 | 5.00 |
| 599.80 | 5.50 | 5.50 |
| 550.93 | 4.75 | 4.75 |
| 597.01 | 6.41 | 6.41 |
| 495.95 | 4.37 | 4.37 |
| 475.94 | 3.92 | 3.92 |
| 516.95 | 4.94 | 4.94 |
| 564.92 | 4.44 | 4.44 |
| 516.95 | 4.91 | 4.91 |
| 506.99 | 3.50 | 3.50 |
| 502.92 | 4.60 | 4.60 |
| 590.97 | 4.97 | 4.97 |