Basic Information
ID: ALA5052858
Type: Binding
Description: Inhibition of C-terminal FLAG-His-tagged full length human CTPS1 measured after 60 mins by ADP-Glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5052858
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.46 | 2.76 | 2.76 |
| 468.54 | 2.81 | 2.81 |
| 488.55 | 3.15 | 3.15 |
| 486.53 | 3.12 | 3.12 |
| 470.98 | 4.62 | 4.62 |
| 524.50 | 3.91 | 3.91 |
| 536.54 | 3.91 | 3.91 |
| 512.59 | 3.16 | 3.16 |
| 462.54 | 3.23 | 3.23 |
| 470.56 | 3.01 | 3.01 |
| 480.59 | 4.36 | 4.36 |
| 486.53 | 2.95 | 2.95 |
| 437.53 | 3.36 | 3.36 |
| 488.55 | 3.15 | 3.15 |
| 505.52 | 4.59 | 4.59 |
| 497.58 | 2.94 | 2.94 |
| 475.51 | 2.15 | 2.15 |
| 480.55 | 2.91 | 2.91 |
| 501.54 | 2.69 | 2.69 |
| 500.56 | 3.29 | 3.29 |
| 517.01 | 3.81 | 3.81 |
| 514.58 | 3.60 | 3.60 |
| 478.46 | 3.04 | 3.04 |
| 455.52 | 3.50 | 3.50 |
| 510.62 | 3.93 | 3.93 |
| 504.53 | 4.98 | 4.98 |
| 513.60 | 4.29 | 4.29 |
| 487.56 | 3.75 | 3.75 |
| 507.50 | 3.38 | 3.38 |
| 472.96 | 3.62 | 3.62 |
| 553.54 | 4.66 | 4.66 |
| 512.59 | 3.00 | 3.00 |
| 496.45 | 3.18 | 3.18 |
| 508.48 | 2.96 | 2.96 |
| 438.51 | 2.97 | 2.97 |
| 505.52 | 4.38 | 4.38 |
| 528.61 | 4.07 | 4.07 |
| 496.59 | 3.46 | 3.46 |
| 409.47 | 2.62 | 2.62 |
| 423.50 | 3.18 | 3.18 |
| 494.50 | 3.55 | 3.55 |
| 524.50 | 4.13 | 4.13 |
| 438.51 | 2.75 | 2.75 |
| 482.57 | 3.15 | 3.15 |
| 440.49 | 2.03 | 2.03 |
| 496.59 | 3.54 | 3.54 |
| 482.57 | 3.15 | 3.15 |
| 468.54 | 2.98 | 2.98 |
| 510.62 | 3.77 | 3.77 |
| 438.51 | 2.97 | 2.97 |
| 510.62 | 3.85 | 3.85 |
| 514.58 | 3.68 | 3.68 |
| 507.58 | 3.02 | 3.02 |
| 506.51 | 3.77 | 3.77 |
| 483.55 | 2.76 | 2.76 |
| 408.48 | 3.23 | 3.23 |
| 506.51 | 3.99 | 3.99 |
| 535.55 | 4.52 | 4.52 |
| 461.55 | 3.84 | 3.84 |
| 500.56 | 3.29 | 3.29 |
| 456.53 | 2.62 | 2.62 |
| 510.62 | 3.77 | 3.77 |
| 438.51 | 2.75 | 2.75 |
| 506.51 | 3.99 | 3.99 |
| 497.58 | 3.15 | 3.15 |
| 455.52 | 3.71 | 3.71 |
| 480.47 | 3.24 | 3.24 |
| 462.54 | 3.45 | 3.45 |
| 438.51 | 2.75 | 2.75 |
| 500.56 | 3.51 | 3.51 |
| 495.61 | 4.15 | 4.15 |
| 477.47 | 3.64 | 3.64 |
| 451.55 | 3.67 | 3.67 |
| 518.55 | 3.43 | 3.43 |
| 498.61 | 3.79 | 3.79 |
| 437.53 | 3.58 | 3.58 |
| 440.53 | 2.84 | 2.84 |
| 497.58 | 2.94 | 2.94 |
| 468.54 | 2.76 | 2.76 |
| 483.55 | 2.55 | 2.55 |
| 495.57 | 2.69 | 2.69 |
| 496.59 | 3.54 | 3.54 |
| 508.60 | 3.69 | 3.69 |
| 520.54 | 4.08 | 4.08 |
| 494.58 | 3.30 | 3.30 |
| 471.97 | 4.01 | 4.01 |
| 467.55 | 3.37 | 3.37 |
| 496.59 | 3.54 | 3.54 |
| 530.58 | 3.30 | 3.30 |
| 481.58 | 3.76 | 3.76 |
| 507.49 | 3.57 | 3.57 |
| 554.53 | 4.05 | 4.05 |
| 507.50 | 3.17 | 3.17 |
| 496.59 | 3.76 | 3.76 |
| 457.52 | 2.02 | 2.02 |
| 536.54 | 3.91 | 3.91 |
| 482.57 | 3.37 | 3.37 |
| 489.96 | 4.37 | 4.37 |
| 456.50 | 2.89 | 2.89 |
| 454.51 | 2.42 | 2.42 |
| 514.58 | 3.90 | 3.90 |
| 566.56 | 4.05 | 4.05 |
| 471.97 | 4.23 | 4.23 |
| 495.61 | 4.36 | 4.36 |
| 456.50 | 3.11 | 3.11 |
| 482.57 | 3.15 | 3.15 |
| 514.58 | 3.60 | 3.60 |
| 503.53 | 3.96 | 3.96 |
| 455.52 | 3.50 | 3.50 |
| 494.50 | 3.63 | 3.63 |
| 513.60 | 4.50 | 4.50 |