Basic Information
ID: ALA5053344
Type: Binding
Description: Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5053344
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 565.65 | 2.78 | 2.78 |
| 545.66 | 4.62 | 4.62 |
| 493.61 | 2.85 | 2.85 |
| 549.64 | 3.68 | 3.68 |
| 565.65 | 2.78 | 2.78 |
| 529.64 | 4.23 | 4.23 |
| 566.64 | 2.18 | 2.18 |
| 545.67 | 1.77 | 1.77 |
| 501.58 | 3.45 | 3.45 |
| 523.64 | 2.21 | 2.21 |
| 545.66 | 4.62 | 4.62 |
| 546.64 | 3.98 | 3.98 |
| 543.62 | 3.22 | 3.22 |
| 545.66 | 4.62 | 4.62 |
| 527.62 | 4.25 | 4.25 |
| 565.65 | 2.78 | 2.78 |
| 545.66 | 4.62 | 4.62 |
| 546.64 | 3.98 | 3.98 |
| 507.64 | 3.24 | 3.24 |
| 530.62 | 3.63 | 3.63 |
| 530.62 | 3.63 | 3.63 |
| 509.66 | 3.22 | 3.22 |
| 566.64 | 2.18 | 2.18 |