Assay Report Card

Basic Information

ID: ALA5053346

Type: Binding

Description: Inhibition of 50 nM of HSD17B13 (unknown origin) using LTB4 as substrate incubated for 1 or 2 hrs and measured after 1 hr by NADH Glo luminescence assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
460.414.044.04
401.343.723.72
394.393.603.60
384.364.204.20
414.384.644.64
378.394.154.15
401.393.373.37
420.946.276.27
400.404.484.48
432.474.944.94
452.485.875.87
481.265.975.97
498.514.054.05
455.484.384.38
390.363.843.84
389.332.602.60
462.453.623.62
440.425.295.29
368.383.673.67
392.424.694.69
518.546.426.42
352.312.952.95
497.525.635.63
407.783.963.96
401.393.923.92
408.773.363.36
414.384.644.64
396.413.993.99
426.445.185.18
408.423.993.99
512.534.394.39
480.493.213.21
442.394.134.13
374.322.702.70
562.336.306.30
484.425.485.48
539.544.744.74
336.273.703.70
507.474.994.99
449.434.984.98
471.295.685.68
625.537.347.34
402.373.413.41
364.373.763.76
493.285.405.40
439.225.205.20
416.404.234.23
541.354.444.44
339.272.042.04
402.404.384.38
546.573.093.09
392.424.544.54
442.445.205.20
360.413.933.93
380.373.733.73
465.453.283.28
349.313.453.45
412.414.954.95
392.383.693.69
451.454.324.32
478.493.883.88
362.353.843.84
420.774.674.67
434.804.984.98
380.373.733.73
380.372.812.81
538.494.604.60
514.574.404.40
401.343.723.72
426.445.175.17
408.424.244.24
428.414.944.94
416.404.234.23
428.414.244.24
368.383.673.67
365.362.972.97
411.343.893.89
496.536.686.68
387.323.413.41
416.404.234.23
366.342.692.69
415.374.034.03
540.524.134.13
366.342.422.42
492.465.095.09
366.343.223.22
506.556.666.66
428.455.095.09
380.373.733.73
364.373.763.76
442.444.424.42
426.444.794.79
338.292.652.65
470.503.663.66
384.414.304.30
449.434.984.98
416.404.234.23
414.383.853.85
394.393.603.60
509.355.765.76
408.424.244.24
402.373.923.92
411.343.893.89
494.516.596.59
428.414.944.94
310.283.213.21
430.383.913.91
379.383.403.40
442.445.145.14
335.293.443.44
322.292.812.81
393.414.164.16
404.324.164.16
352.312.962.96
448.423.373.37
386.374.224.22
324.303.193.19
394.393.603.60
336.313.123.12
444.464.314.31
310.282.632.63
394.394.124.12
497.525.635.63
382.383.333.33
462.453.683.68
449.434.984.98
394.393.853.85
366.343.003.00
432.474.944.94
367.373.953.95
412.414.874.87
410.464.844.84
366.364.484.48
380.373.463.46
387.363.503.50
412.374.664.66
495.286.056.05
550.386.236.23
352.313.043.04
460.414.344.34
366.384.554.55
490.486.306.30
442.445.205.20
400.404.534.53
393.414.164.16
538.325.695.69
462.454.394.39
430.434.484.48
428.445.025.02
492.465.095.09
428.413.993.99
454.455.365.36
400.404.484.48
538.325.695.69
394.425.125.12
414.384.644.64
352.312.952.95
426.394.904.90
432.474.944.94
387.224.314.31
512.534.044.04
495.505.015.01
444.485.305.30
351.332.992.99
447.443.973.97
356.733.463.46
530.145.445.44
386.334.024.02
392.383.693.69
455.444.054.05
505.505.095.09
354.353.283.28
372.353.913.91
365.362.972.97
380.373.733.73
526.564.784.78
428.414.944.94
593.416.606.60
393.414.164.16
499.494.474.47
469.515.825.82
432.474.944.94
350.343.373.37
454.495.965.96
380.373.733.73
414.434.314.31
428.393.953.95
415.423.633.63
444.454.064.06
462.453.683.68
298.222.352.35
360.413.933.93
378.394.464.46
474.505.205.20
380.373.733.73
428.455.115.11
506.486.436.43
420.774.674.67
536.396.126.12
442.445.205.20
492.483.173.17
440.344.934.93
392.424.544.54
412.844.884.88
406.794.574.57
428.414.974.97
400.363.813.81
396.372.832.83
413.403.523.52
400.404.784.78
491.475.705.70
512.534.804.80
400.364.334.33
430.454.994.99
422.373.663.66
400.363.903.90
394.394.124.12
366.343.133.13
330.393.443.44
468.355.125.12
408.773.363.36
413.403.883.88
483.275.895.89
454.375.245.24
441.245.225.22
378.394.154.15
338.292.572.57
414.434.784.78
450.424.374.37
396.374.404.40
394.393.853.85
504.365.125.12
438.455.485.48
444.485.335.33
387.323.413.41
402.333.303.30
507.546.066.06
396.434.454.45
476.483.983.98
414.434.874.87
390.363.843.84
398.434.604.60
398.384.514.51
430.454.944.94
427.434.274.27
456.465.595.59
380.373.523.52
456.214.724.72
417.343.423.42
483.275.895.89
398.384.564.56
522.485.705.70
412.464.914.91
562.336.306.30
497.306.286.28
364.373.973.97
386.374.224.22
491.475.175.17
365.311.801.80
366.343.343.34
456.465.595.59
366.343.133.13
428.413.993.99
400.404.534.53
420.774.674.67
465.435.105.10
504.516.236.23
376.384.374.37
440.475.265.26
455.225.335.33
352.312.912.91
378.394.364.36
450.424.374.37
388.474.744.74
509.535.355.35
440.425.285.28
479.504.274.27
404.324.164.16
432.474.944.94
366.342.742.74
491.475.705.70
481.265.975.97
540.345.715.71
432.474.944.94
485.514.744.74
401.343.723.72
427.433.563.56
414.384.584.58
358.753.933.93
434.804.984.98
483.275.895.89
434.804.984.98
398.434.474.47
456.465.595.59
380.373.733.73
398.384.514.51
441.245.225.22
417.343.423.42
416.404.234.23
402.373.923.92
504.516.236.23
469.255.635.63
455.225.335.33
490.486.306.30
382.342.442.44
464.473.633.63
494.516.596.59
365.363.013.01
491.475.705.70
398.814.494.49
397.363.783.78
363.343.803.80
349.313.453.45
498.505.535.53
382.374.114.11
416.404.234.23
457.453.753.75
407.783.963.96
415.374.034.03
407.783.963.96
380.373.463.46
453.464.294.29
455.444.054.05
352.312.822.82
412.414.644.64
370.333.893.89
411.343.893.89
496.495.445.44
400.364.334.33
471.265.985.98
386.374.224.22
528.604.754.75
364.374.074.07
415.424.264.26
412.414.404.40
428.414.944.94
440.424.334.33
455.484.904.90
427.434.274.27
450.424.374.37
380.372.742.74
468.355.125.12
416.364.034.03
393.372.542.54
415.423.983.98
378.394.154.15
442.445.145.14
429.453.893.89
362.354.104.10
380.373.543.54
415.424.264.26
410.464.844.84
516.424.164.16
382.374.254.25
416.404.234.23
440.475.575.57
471.484.404.40
464.473.633.63
336.313.123.12
441.413.713.71
416.424.694.69
365.363.383.38
382.383.333.33
456.465.595.59
368.343.943.94
400.364.334.33
457.454.364.36
403.323.123.12
456.464.814.81
426.445.025.02
406.404.124.12
508.345.955.95
351.332.782.78
364.373.763.76
363.343.503.50
380.372.812.81
399.373.993.99
559.615.425.42
338.292.522.52
398.434.604.60
464.473.633.63
442.445.205.20
400.404.534.53
361.323.073.07
434.403.063.06
508.535.455.45
496.536.686.68
392.424.754.75
456.473.323.32
396.434.454.45
387.323.413.41
348.282.752.75
471.295.685.68
420.774.674.67
402.494.914.91
380.394.734.73
546.504.594.59
446.384.044.04
540.345.715.71
497.306.286.28
366.343.213.21
414.434.784.78
380.373.133.13
446.384.044.04
384.364.204.20
414.434.874.87
432.403.933.93
398.384.564.56
440.425.285.28
350.343.513.51
464.473.633.63
365.363.383.38
476.484.014.01
454.375.025.02
387.323.413.41
396.444.764.76
442.394.134.13
296.252.952.95
374.403.643.64
433.413.783.78
414.384.584.58
354.353.363.36
429.403.873.87
382.414.064.06
400.404.534.53
437.423.623.62
412.414.954.95
380.373.463.46
351.332.702.70
348.283.503.50
469.514.724.72
396.413.993.99
491.475.705.70
414.435.045.04
483.275.895.89
378.394.454.45
414.384.644.64
379.342.152.15
401.343.723.72
588.635.965.96
430.454.994.99
438.334.914.91
499.494.474.47
428.414.034.03
440.344.934.93
400.404.534.53
338.292.572.57
347.303.383.38
432.424.394.39
388.353.623.62
350.343.373.37
466.465.775.77
337.302.682.68
352.312.962.96
492.465.095.09
401.393.923.92
438.455.375.37
365.362.662.66
366.343.003.00
393.414.164.16
382.414.454.45
440.344.934.93
378.394.154.15
444.414.134.13
401.343.723.72
393.453.863.86
364.373.763.76
408.773.363.36
537.505.655.65
422.485.285.28
352.363.973.97
338.292.522.52
398.384.014.01
400.404.534.53
378.394.154.15
382.414.064.06
426.394.754.75
316.673.303.30
400.364.334.33
471.484.704.70
469.255.635.63
349.313.743.74
407.323.153.15
394.393.743.74
404.343.323.32
436.845.035.03
518.546.426.42
530.575.555.55
392.424.754.75
418.373.503.50
384.363.943.94
456.495.645.64
446.434.104.10
446.495.205.20
388.353.623.62
394.393.603.60
420.824.764.76
434.425.985.98
514.505.195.19
398.384.514.51
460.484.494.49
578.407.017.01
502.345.105.10
406.455.005.00
452.234.074.07
495.286.056.05
456.214.724.72
403.323.123.12
393.413.793.79
485.514.604.60
441.413.713.71
527.616.746.74
376.383.933.93
414.434.844.84
521.505.715.71
380.373.733.73
420.824.874.87
348.283.503.50
366.343.213.21
406.404.124.12
384.794.104.10
454.454.724.72
433.413.783.78
406.314.174.17
430.383.913.91
351.332.992.99
444.414.134.13
380.373.733.73
440.474.994.99
417.414.634.63
364.373.763.76
457.245.425.42
408.334.194.19
336.313.203.20
408.773.363.36
414.383.853.85
497.306.286.28
396.394.554.55
387.224.314.31
366.343.343.34
429.443.973.97
469.255.635.63
497.306.286.28
454.375.025.02
380.373.733.73
507.546.066.06
350.343.513.51
507.474.994.99
366.343.343.34
406.455.145.14
417.343.423.42
382.374.254.25
414.384.584.58
376.384.374.37
469.255.635.63
448.445.585.58
455.225.335.33
366.343.343.34
471.483.903.90
366.343.343.34
438.415.305.30
427.433.563.56
401.343.723.72
454.455.365.36