Basic Information
ID: ALA5053349
Type: ADME
Description: Metabolic stability in human liver microsomes at 1 uM assessed as compound remaining incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5053349
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.39 | 4.15 | 4.15 |
| 400.40 | 4.48 | 4.48 |
| 414.38 | 4.64 | 4.64 |
| 364.37 | 3.76 | 3.76 |
| 392.42 | 4.54 | 4.54 |
| 380.37 | 3.73 | 3.73 |
| 465.45 | 3.28 | 3.28 |
| 434.80 | 4.98 | 4.98 |
| 408.42 | 4.24 | 4.24 |
| 506.55 | 6.66 | 6.66 |
| 364.37 | 3.76 | 3.76 |
| 406.79 | 4.57 | 4.57 |
| 393.41 | 4.16 | 4.16 |
| 386.37 | 4.22 | 4.22 |
| 310.28 | 2.63 | 2.63 |
| 394.39 | 3.85 | 3.85 |
| 366.34 | 3.00 | 3.00 |
| 393.41 | 4.16 | 4.16 |
| 462.45 | 4.39 | 4.39 |
| 386.33 | 4.02 | 4.02 |
| 372.35 | 3.91 | 3.91 |
| 393.41 | 4.16 | 4.16 |
| 388.35 | 3.62 | 3.62 |
| 380.37 | 3.73 | 3.73 |
| 414.43 | 4.31 | 4.31 |
| 428.39 | 3.95 | 3.95 |
| 428.45 | 5.11 | 5.11 |
| 440.34 | 4.93 | 4.93 |
| 392.42 | 4.54 | 4.54 |
| 412.84 | 4.88 | 4.88 |
| 406.79 | 4.57 | 4.57 |
| 430.45 | 4.99 | 4.99 |
| 441.24 | 5.22 | 5.22 |
| 394.39 | 3.85 | 3.85 |
| 507.54 | 6.06 | 6.06 |
| 414.43 | 4.87 | 4.87 |
| 364.37 | 3.97 | 3.97 |
| 386.37 | 4.22 | 4.22 |
| 366.34 | 3.34 | 3.34 |
| 400.40 | 4.53 | 4.53 |
| 465.43 | 5.10 | 5.10 |
| 455.22 | 5.33 | 5.33 |
| 352.31 | 2.91 | 2.91 |
| 378.39 | 4.36 | 4.36 |
| 366.34 | 2.74 | 2.74 |
| 434.80 | 4.98 | 4.98 |
| 380.37 | 3.73 | 3.73 |
| 402.37 | 3.92 | 3.92 |
| 455.22 | 5.33 | 5.33 |
| 382.34 | 2.44 | 2.44 |
| 398.81 | 4.49 | 4.49 |
| 380.37 | 3.46 | 3.46 |
| 352.31 | 2.82 | 2.82 |
| 370.33 | 3.89 | 3.89 |
| 378.39 | 4.15 | 4.15 |
| 380.37 | 3.54 | 3.54 |
| 508.34 | 5.95 | 5.95 |
| 351.33 | 2.78 | 2.78 |
| 366.34 | 3.21 | 3.21 |
| 416.36 | 3.64 | 3.64 |
| 432.40 | 3.93 | 3.93 |
| 350.34 | 3.51 | 3.51 |
| 365.36 | 3.38 | 3.38 |
| 334.38 | 2.91 | 2.91 |
| 382.41 | 4.06 | 4.06 |
| 348.28 | 3.50 | 3.50 |
| 414.43 | 5.04 | 5.04 |
| 400.40 | 4.53 | 4.53 |
| 347.30 | 3.38 | 3.38 |
| 388.35 | 3.62 | 3.62 |
| 352.31 | 2.96 | 2.96 |
| 366.34 | 3.00 | 3.00 |
| 393.41 | 4.16 | 4.16 |
| 440.34 | 4.93 | 4.93 |
| 378.39 | 4.15 | 4.15 |
| 388.35 | 3.62 | 3.62 |
| 420.82 | 4.76 | 4.76 |
| 514.50 | 5.19 | 5.19 |
| 398.38 | 4.51 | 4.51 |
| 384.79 | 4.10 | 4.10 |
| 386.37 | 4.22 | 4.22 |
| 454.37 | 5.02 | 5.02 |
| 417.34 | 3.42 | 3.42 |
| 376.38 | 4.37 | 4.37 |
| 448.44 | 5.58 | 5.58 |