Basic Information
ID: ALA5053354
Type: Binding
Description: Inhibition of HSD17B2 (unknown origin) using estradiol as substrate incubated for 45 mins and measured after 1 hr by NADH Glo luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5053354
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.34 | 3.72 | 3.72 |
| 384.36 | 4.20 | 4.20 |
| 378.39 | 4.15 | 4.15 |
| 400.40 | 4.48 | 4.48 |
| 497.52 | 5.63 | 5.63 |
| 414.38 | 4.64 | 4.64 |
| 512.53 | 4.39 | 4.39 |
| 392.42 | 4.54 | 4.54 |
| 434.80 | 4.98 | 4.98 |
| 401.34 | 3.72 | 3.72 |
| 408.42 | 4.24 | 4.24 |
| 415.37 | 4.03 | 4.03 |
| 492.46 | 5.09 | 5.09 |
| 506.55 | 6.66 | 6.66 |
| 364.37 | 3.76 | 3.76 |
| 426.44 | 4.79 | 4.79 |
| 449.43 | 4.98 | 4.98 |
| 406.79 | 4.57 | 4.57 |
| 322.29 | 2.81 | 2.81 |
| 386.37 | 4.22 | 4.22 |
| 444.46 | 4.31 | 4.31 |
| 394.39 | 4.12 | 4.12 |
| 366.38 | 4.55 | 4.55 |
| 490.48 | 6.30 | 6.30 |
| 462.45 | 4.39 | 4.39 |
| 492.46 | 5.09 | 5.09 |
| 454.45 | 5.36 | 5.36 |
| 394.42 | 5.12 | 5.12 |
| 414.38 | 4.64 | 4.64 |
| 426.39 | 4.90 | 4.90 |
| 386.33 | 4.02 | 4.02 |
| 499.49 | 4.47 | 4.47 |
| 414.43 | 4.31 | 4.31 |
| 378.39 | 4.46 | 4.46 |
| 440.34 | 4.93 | 4.93 |
| 406.79 | 4.57 | 4.57 |
| 430.45 | 4.99 | 4.99 |
| 400.36 | 3.90 | 3.90 |
| 441.24 | 5.22 | 5.22 |
| 394.39 | 3.85 | 3.85 |
| 504.36 | 5.12 | 5.12 |
| 507.54 | 6.06 | 6.06 |
| 412.46 | 4.91 | 4.91 |
| 497.30 | 6.28 | 6.28 |
| 386.37 | 4.22 | 4.22 |
| 366.34 | 3.34 | 3.34 |
| 400.40 | 4.53 | 4.53 |
| 504.51 | 6.23 | 6.23 |
| 455.22 | 5.33 | 5.33 |
| 352.31 | 2.91 | 2.91 |
| 509.53 | 5.35 | 5.35 |
| 414.38 | 3.94 | 3.94 |
| 366.34 | 2.74 | 2.74 |
| 491.47 | 5.70 | 5.70 |
| 432.47 | 4.94 | 4.94 |
| 434.80 | 4.98 | 4.98 |
| 456.46 | 5.59 | 5.59 |
| 402.37 | 3.92 | 3.92 |
| 455.22 | 5.33 | 5.33 |
| 382.34 | 2.44 | 2.44 |
| 494.51 | 6.59 | 6.59 |
| 397.36 | 3.78 | 3.78 |
| 498.50 | 5.53 | 5.53 |
| 370.33 | 3.89 | 3.89 |
| 411.34 | 3.89 | 3.89 |
| 364.37 | 4.07 | 4.07 |
| 468.35 | 5.12 | 5.12 |
| 415.42 | 4.26 | 4.26 |
| 406.40 | 4.12 | 4.12 |
| 508.34 | 5.95 | 5.95 |
| 351.33 | 2.78 | 2.78 |
| 399.37 | 3.99 | 3.99 |
| 442.44 | 5.20 | 5.20 |
| 496.53 | 6.68 | 6.68 |
| 392.42 | 4.75 | 4.75 |
| 420.77 | 4.67 | 4.67 |
| 380.39 | 4.73 | 4.73 |
| 432.40 | 3.93 | 3.93 |
| 398.38 | 4.56 | 4.56 |
| 440.42 | 5.28 | 5.28 |
| 433.41 | 3.78 | 3.78 |
| 348.28 | 3.50 | 3.50 |
| 491.47 | 5.70 | 5.70 |
| 414.38 | 4.64 | 4.64 |
| 438.33 | 4.91 | 4.91 |
| 347.30 | 3.38 | 3.38 |
| 388.35 | 3.62 | 3.62 |
| 352.31 | 2.96 | 2.96 |
| 492.46 | 5.09 | 5.09 |
| 366.34 | 3.00 | 3.00 |
| 393.41 | 4.16 | 4.16 |
| 401.34 | 3.72 | 3.72 |
| 400.36 | 4.33 | 4.33 |
| 518.54 | 6.42 | 6.42 |
| 446.43 | 4.10 | 4.10 |
| 420.82 | 4.76 | 4.76 |
| 514.50 | 5.19 | 5.19 |
| 398.38 | 4.51 | 4.51 |
| 414.43 | 4.84 | 4.84 |
| 380.37 | 3.73 | 3.73 |
| 433.41 | 3.78 | 3.78 |
| 406.31 | 4.17 | 4.17 |
| 430.38 | 3.91 | 3.91 |
| 386.37 | 4.22 | 4.22 |
| 366.34 | 3.34 | 3.34 |
| 454.37 | 5.02 | 5.02 |
| 380.37 | 3.73 | 3.73 |
| 507.54 | 6.06 | 6.06 |
| 366.34 | 3.34 | 3.34 |
| 406.45 | 5.14 | 5.14 |
| 417.34 | 3.42 | 3.42 |
| 414.38 | 4.58 | 4.58 |
| 448.44 | 5.58 | 5.58 |