Basic Information
ID: ALA5053379
Type: Binding
Description: Inhibition of METTL3-mediated m6A methylation in human MOLM-13 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: MOLM-13
Activity Charts
Bioactivity
Activity Types for Assay ALA5053379
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.56 | 4.36 | 4.36 |
| 493.57 | 4.59 | 4.59 |
| 559.68 | 5.33 | 5.33 |
| 411.47 | 3.67 | 3.67 |
| 489.59 | 4.56 | 4.56 |
| 466.55 | 4.62 | 4.62 |
| 469.55 | 4.15 | 4.15 |
| 547.67 | 4.75 | 4.75 |
| 477.53 | 5.14 | 5.14 |
| 550.63 | 3.94 | 3.94 |
| 431.89 | 4.22 | 4.22 |
| 411.47 | 4.08 | 4.08 |
| 397.44 | 3.77 | 3.77 |
| 547.62 | 4.24 | 4.24 |
| 578.70 | 4.81 | 4.81 |
| 465.56 | 5.22 | 5.22 |
| 580.67 | 4.60 | 4.60 |
| 712.71 | 3.96 | 3.96 |
| 426.48 | 3.87 | 3.87 |
| 561.69 | 4.78 | 4.78 |
| 479.59 | 5.33 | 5.33 |
| 411.47 | 3.88 | 3.88 |
| 505.59 | 4.53 | 4.53 |
| 467.53 | 4.42 | 4.42 |
| 432.88 | 3.62 | 3.62 |
| 464.58 | 4.83 | 4.83 |
| 477.53 | 3.97 | 3.97 |
| 411.47 | 3.88 | 3.88 |
| 497.61 | 4.02 | 4.02 |
| 397.44 | 3.57 | 3.57 |
| 460.93 | 4.32 | 4.32 |
| 451.53 | 4.52 | 4.52 |
| 494.60 | 4.06 | 4.06 |
| 398.43 | 2.96 | 2.96 |
| 560.67 | 3.90 | 3.90 |
| 445.91 | 4.32 | 4.32 |
| 524.63 | 3.83 | 3.83 |
| 428.93 | 5.03 | 5.03 |
| 519.61 | 4.55 | 4.55 |
| 465.56 | 5.36 | 5.36 |
| 457.93 | 4.39 | 4.39 |
| 574.74 | 4.69 | 4.69 |
| 545.65 | 5.09 | 5.09 |
| 481.56 | 3.92 | 3.92 |
| 395.47 | 3.77 | 3.77 |
| 445.91 | 4.61 | 4.61 |
| 491.60 | 4.79 | 4.79 |
| 475.56 | 4.17 | 4.17 |
| 467.53 | 4.42 | 4.42 |
| 501.60 | 4.34 | 4.34 |
| 508.63 | 4.77 | 4.77 |