Basic Information
ID: ALA5053381
Type: Binding
Description: Inhibition of METTL1 (unknown origin) using GCCGAGAUAGCUCAGUUGGGAGAGCGUUAGACUGAAGAUCUAAAGGUCCCUG GUUCAAUCCCGGGUUUCGGCA-biotin and 3H-SAM as substrates preincubated for 5 mins followed by substrate addition incubated for 20 mins by TopCount scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5053381
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.56 | 4.36 | 4.36 |
| 436.52 | 5.05 | 5.05 |
| 473.92 | 3.92 | 3.92 |
| 411.47 | 4.13 | 4.13 |
| 465.56 | 4.86 | 4.86 |
| 483.58 | 3.46 | 3.46 |
| 467.53 | 4.55 | 4.55 |
| 461.53 | 3.71 | 3.71 |
| 444.93 | 5.22 | 5.22 |
| 388.48 | 2.64 | 2.64 |
| 439.52 | 4.40 | 4.40 |
| 396.45 | 4.38 | 4.38 |
| 438.90 | 3.68 | 3.68 |
| 466.55 | 4.62 | 4.62 |
| 459.94 | 4.78 | 4.78 |
| 469.55 | 4.15 | 4.15 |
| 505.63 | 5.78 | 5.78 |
| 383.42 | 3.11 | 3.11 |
| 547.67 | 4.75 | 4.75 |
| 416.87 | 4.37 | 4.37 |
| 477.53 | 5.14 | 5.14 |
| 469.55 | 4.35 | 4.35 |
| 517.49 | 3.63 | 3.63 |
| 500.44 | 2.89 | 2.89 |
| 425.50 | 4.13 | 4.13 |
| 431.89 | 4.22 | 4.22 |
| 494.60 | 4.38 | 4.38 |
| 397.44 | 3.57 | 3.57 |
| 446.90 | 4.53 | 4.53 |
| 448.89 | 4.96 | 4.96 |
| 494.65 | 4.66 | 4.66 |
| 430.90 | 4.67 | 4.67 |
| 450.55 | 5.12 | 5.12 |
| 464.57 | 5.83 | 5.83 |
| 482.59 | 4.06 | 4.06 |
| 572.72 | 5.81 | 5.81 |
| 426.48 | 3.87 | 3.87 |
| 561.69 | 4.78 | 4.78 |
| 479.59 | 5.33 | 5.33 |
| 431.89 | 4.22 | 4.22 |
| 384.40 | 2.82 | 2.82 |
| 411.47 | 3.88 | 3.88 |
| 467.53 | 4.42 | 4.42 |
| 432.88 | 3.62 | 3.62 |
| 540.43 | 4.48 | 4.48 |
| 474.37 | 4.97 | 4.97 |
| 414.44 | 4.31 | 4.31 |
| 464.58 | 4.83 | 4.83 |
| 426.48 | 3.66 | 3.66 |
| 448.89 | 4.96 | 4.96 |
| 426.48 | 3.63 | 3.63 |
| 421.46 | 4.04 | 4.04 |
| 477.53 | 3.97 | 3.97 |
| 467.58 | 4.28 | 4.28 |
| 491.60 | 5.39 | 5.39 |
| 464.49 | 4.22 | 4.22 |
| 515.57 | 5.86 | 5.86 |
| 411.47 | 3.88 | 3.88 |
| 413.46 | 3.91 | 3.91 |
| 497.61 | 4.02 | 4.02 |
| 460.93 | 4.32 | 4.32 |
| 430.90 | 4.83 | 4.83 |
| 451.53 | 4.52 | 4.52 |
| 515.57 | 5.32 | 5.32 |
| 446.90 | 3.80 | 3.80 |
| 494.60 | 4.06 | 4.06 |
| 398.43 | 2.96 | 2.96 |
| 551.94 | 4.28 | 4.28 |
| 432.88 | 3.62 | 3.62 |
| 560.67 | 3.90 | 3.90 |
| 509.80 | 5.59 | 5.59 |
| 437.92 | 4.28 | 4.28 |
| 470.96 | 5.61 | 5.61 |
| 428.93 | 5.03 | 5.03 |
| 465.56 | 5.36 | 5.36 |
| 514.44 | 4.84 | 4.84 |
| 488.39 | 4.99 | 4.99 |
| 478.97 | 4.24 | 4.24 |
| 465.56 | 5.08 | 5.08 |
| 505.63 | 5.78 | 5.78 |
| 395.47 | 3.77 | 3.77 |
| 503.61 | 4.74 | 4.74 |
| 431.89 | 4.22 | 4.22 |
| 491.60 | 4.79 | 4.79 |
| 396.45 | 4.17 | 4.17 |
| 460.93 | 4.26 | 4.26 |
| 475.56 | 4.17 | 4.17 |
| 467.53 | 4.42 | 4.42 |
| 462.31 | 3.87 | 3.87 |
| 483.55 | 5.36 | 5.36 |
| 467.53 | 4.42 | 4.42 |
| 425.50 | 4.23 | 4.23 |
| 396.45 | 4.02 | 4.02 |
| 508.63 | 4.77 | 4.77 |