Assay Report Card

Basic Information

ID: ALA5053385

Type: Binding

Description: Inhibition of recombinant rat/human ADAMTS12 hybrid using HiLyteFluor-488 DELSSMVLELRGLRT-K(QXL520)-E-NH2 as substrate incubated for 120 mins and measured by FRET assay

Activity Charts

Bioactivity

Activity Types for Assay ALA5053385

IC50

Total(160)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
377.36	0.13	0.13
365.35	-0.14	-0.14
346.32	0.12	0.12
374.38	0.76	0.76
426.33	1.14	1.14
354.37	0.38	0.38
358.33	1.20	1.20
392.78	0.78	0.78
394.37	0.87	0.87
384.40	0.00	0.00
429.44	0.94	0.94
377.36	0.13	0.13
358.33	0.12	0.12
374.38	0.90	0.90
356.39	0.77	0.77
396.33	0.65	0.65
376.32	0.26	0.26
368.40	0.62	0.62
341.33	-0.62	-0.62
390.35	0.65	0.65
377.31	-0.34	-0.34
370.37	-0.01	-0.01
380.37	-0.53	-0.53
372.36	0.51	0.51
367.37	0.10	0.10
398.36	-0.40	-0.40
397.42	0.60	0.60
354.37	0.29	0.29
342.36	0.23	0.23
392.78	0.78	0.78
392.78	0.49	0.49
435.83	0.98	0.98
374.38	0.76	0.76
339.36	0.59	0.59
359.32	0.59	0.59
400.41	1.29	1.29
412.39	0.09	0.09
435.83	0.98	0.98
415.41	0.64	0.64
401.38	0.33	0.33
401.38	0.33	0.33
344.33	-0.21	-0.21
358.33	0.12	0.12
358.36	-0.80	-0.80
384.40	0.67	0.67
442.37	1.78	1.78
401.38	0.33	0.33
409.23	1.29	1.29
424.38	1.64	1.64
374.38	0.76	0.76
418.44	-0.61	-0.61
416.35	-0.26	-0.26
378.34	0.51	0.51
469.38	1.35	1.35
356.38	1.70	1.70
394.79	1.02	1.02
355.35	0.84	0.84
378.34	0.51	0.51
360.35	0.37	0.37
384.40	0.00	0.00
354.37	0.37	0.37
388.82	1.03	1.03
372.36	0.51	0.51
434.34	-0.12	-0.12
332.30	-0.27	-0.27
347.36	-0.56	-0.56
395.35	0.27	0.27
382.42	1.16	1.16
409.23	1.29	1.29
386.39	0.90	0.90
388.82	1.03	1.03
358.33	0.12	0.12
354.37	0.29	0.29
434.34	0.46	0.46
392.78	0.78	0.78
374.79	0.64	0.64
402.39	0.14	0.14
466.36	0.63	0.63
368.40	0.77	0.77
370.41	1.01	1.01
394.31	0.40	0.40
406.81	1.17	1.17
372.36	0.51	0.51
356.39	0.62	0.62
340.34	-0.01	-0.01
360.35	0.37	0.37
354.37	0.29	0.29
419.24	0.75	0.75
359.32	-0.48	-0.48
408.34	0.79	0.79
359.32	-0.48	-0.48
395.35	0.27	0.27
374.79	0.64	0.64
419.37	0.47	0.47
360.35	0.51	0.51
376.32	0.26	0.26
463.35	1.28	1.28
392.78	0.78	0.78
390.35	0.65	0.65
365.35	-0.14	-0.14
441.45	1.20	1.20
419.37	0.47	0.47
355.40	1.23	1.23
408.34	0.76	0.76
415.41	0.64	0.64
398.36	-0.40	-0.40
395.35	0.27	0.27
432.80	0.26	0.26
374.79	0.64	0.64
342.36	0.38	0.38
424.34	0.88	0.88
354.37	0.37	0.37
342.32	-1.22	-1.22
354.37	0.38	0.38
370.37	-0.39	-0.39
376.32	0.26	0.26
379.38	0.25	0.25
406.81	1.17	1.17
376.32	0.22	0.22
340.34	1.06	1.06
394.79	1.02	1.02
376.32	0.26	0.26