Basic Information
ID: ALA5053471
Type: Binding
Description: Inhibition of human GOAT expressed in baculovirus infected Sf9 cells at 10 uM using octanoyl-CoA and ghrelin-biotin as substrate preincubated for 20 mins followed by substrate addition and measured after = > 1 hr by HTRF assay relative to control
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5053471
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.36 | 5.01 | 5.01 |
| 409.43 | 5.45 | 5.45 |
| 375.88 | 4.86 | 4.86 |
| 395.40 | 5.14 | 5.14 |
| 355.46 | 4.60 | 4.60 |
| 381.38 | 4.83 | 4.83 |
| 384.38 | 4.17 | 4.17 |
| 453.27 | 5.25 | 5.25 |
| 369.27 | 5.24 | 5.24 |
| 424.31 | 4.53 | 4.53 |
| 379.24 | 5.56 | 5.56 |
| 404.80 | 4.51 | 4.51 |
| 394.30 | 4.96 | 4.96 |
| 353.42 | 4.36 | 4.36 |
| 458.39 | 4.80 | 4.80 |
| 381.28 | 5.72 | 5.72 |
| 447.84 | 5.71 | 5.71 |
| 388.34 | 4.00 | 4.00 |
| 353.20 | 4.52 | 4.52 |
| 402.37 | 4.09 | 4.09 |
| 413.39 | 5.28 | 5.28 |
| 438.35 | 4.88 | 4.88 |
| 393.27 | 5.65 | 5.65 |
| 402.37 | 4.31 | 4.31 |
| 361.85 | 4.77 | 4.77 |
| 415.32 | 4.81 | 4.81 |
| 468.36 | 3.98 | 3.98 |
| 325.43 | 4.33 | 4.33 |
| 429.85 | 5.57 | 5.57 |
| 395.31 | 5.89 | 5.89 |
| 378.25 | 5.00 | 5.00 |
| 395.31 | 5.81 | 5.81 |
| 432.85 | 4.91 | 4.91 |
| 383.32 | 6.13 | 6.13 |
| 395.40 | 5.14 | 5.14 |
| 370.35 | 3.86 | 3.86 |
| 381.25 | 5.14 | 5.14 |
| 380.27 | 4.57 | 4.57 |
| 398.41 | 4.26 | 4.26 |
| 418.82 | 4.60 | 4.60 |
| 341.41 | 3.84 | 3.84 |
| 439.24 | 5.17 | 5.17 |
| 423.46 | 5.53 | 5.53 |
| 364.85 | 3.89 | 3.89 |
| 415.82 | 5.48 | 5.48 |
| 369.20 | 3.28 | 3.28 |
| 418.82 | 4.82 | 4.82 |
| 344.44 | 3.55 | 3.55 |
| 330.41 | 3.46 | 3.46 |
| 429.85 | 5.79 | 5.79 |
| 385.63 | 5.60 | 5.60 |
| 427.42 | 5.37 | 5.37 |
| 401.27 | 3.92 | 3.92 |
| 436.81 | 4.74 | 4.74 |
| 398.41 | 4.34 | 4.34 |
| 416.40 | 4.40 | 4.40 |
| 399.37 | 4.97 | 4.97 |
| 450.27 | 6.14 | 6.14 |
| 382.36 | 4.22 | 4.22 |
| 454.33 | 3.89 | 3.89 |
| 443.87 | 5.88 | 5.88 |
| 464.29 | 6.22 | 6.22 |
| 383.23 | 3.93 | 3.93 |
| 350.83 | 3.80 | 3.80 |
| 433.81 | 5.62 | 5.62 |
| 422.79 | 4.65 | 4.65 |
| 339.39 | 4.27 | 4.27 |
| 399.32 | 5.14 | 5.14 |
| 396.39 | 4.53 | 4.53 |
| 413.39 | 5.06 | 5.06 |
| 409.43 | 5.23 | 5.23 |
| 327.41 | 4.12 | 4.12 |
| 353.20 | 4.52 | 4.52 |
| 367.25 | 5.41 | 5.41 |
| 323.42 | 4.71 | 4.71 |