ID: ALA5053472
Type: Binding
Description: Inhibition of rat aortic smooth muscle cell GCH1 expressed in Escherichia coli assessed as reduction in 7,8-dihydroneoptrein 3'-triphosphate formation using GTP as substrate incubated for 1 hr by LC/MS assay
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA5053472
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
166.14 | -1.19 | -1.19 |
150.14 | -0.17 | -0.17 |
164.17 | 0.26 | 0.26 |
183.20 | -0.48 | -0.48 |
152.12 | -0.96 | -0.96 |
241.28 | -0.03 | -0.03 |
281.34 | 0.75 | 0.75 |
178.19 | 0.15 | 0.15 |
336.42 | 1.43 | 1.43 |
180.17 | -1.18 | -1.18 |
197.22 | -0.10 | -0.10 |
241.25 | 1.69 | 1.69 |
239.30 | 0.74 | 0.74 |
225.28 | 0.73 | 0.73 |
209.21 | -0.65 | -0.65 |
477.57 | 1.94 | 1.94 |
360.40 | 1.77 | 1.77 |