Basic Information
ID: ALA5053563
Type: Binding
Description: Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as inhibition of Ins(1,3,4,5)P4 production using Ins(1,3,4,5)P4 as substrate incubated for 20 mins measured using microplate reader
Format: BAO_0000357
Organism: Homo sapiens
Target: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(ALA2331064)
Document: ALA5053481
Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as inhibition of Ins(1,3,4,5)P4 production using Ins(1,3,4,5)P4 as substrate incubated for 20 mins measured using microplate reader: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5053563
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.07 | -3.37 | -3.37 |
| 220.18 | 1.02 | 1.02 |
| 302.24 | 1.99 | 1.99 |
| 520.39 | 5.30 | 5.30 |
| 278.17 | 0.72 | 0.72 |
| 371.89 | 5.47 | 5.47 |
| 730.08 | 0.18 | 0.18 |
| 790.13 | -0.03 | -0.03 |
| 574.10 | 1.52 | 1.52 |
| 730.08 | 0.18 | 0.18 |
| 634.10 | 0.71 | 0.71 |