ID: ALA5054067
Type: Binding
Description: Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days followed by replacement with fresh medium containing compound and measured after 3 days by QuantiGene assay
Organism: Hepatitis B virus
Cell type: HepG2.2.15
Bioactivity
Activity Types for Assay ALA5054067
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
352.83 | 4.32 | 4.32 |
403.87 | 3.21 | 3.21 |
393.83 | 1.65 | 1.65 |
423.83 | 1.64 | 1.64 |
437.86 | 2.03 | 2.03 |
377.83 | 2.68 | 2.68 |
437.86 | 2.03 | 2.03 |
391.86 | 3.07 | 3.07 |
519.48 | 1.98 | 1.98 |
417.44 | 1.69 | 1.69 |
433.90 | 2.84 | 2.84 |
398.40 | 1.89 | 1.89 |
428.42 | 1.25 | 1.25 |
377.83 | 2.68 | 2.68 |
389.84 | 2.82 | 2.82 |
377.83 | 2.68 | 2.68 |
391.86 | 3.07 | 3.07 |
348.79 | 2.83 | 2.83 |
361.83 | 2.75 | 2.75 |
346.82 | 3.64 | 3.64 |
405.84 | 2.06 | 2.06 |
423.83 | 1.64 | 1.64 |
419.87 | 2.45 | 2.45 |
349.78 | 1.94 | 1.94 |
377.83 | 2.68 | 2.68 |
430.42 | 2.23 | 2.23 |
423.83 | 1.64 | 1.64 |
471.41 | 2.40 | 2.40 |
464.93 | 2.60 | 2.60 |
437.86 | 2.03 | 2.03 |
391.86 | 3.07 | 3.07 |
418.89 | 1.97 | 1.97 |
363.81 | 2.29 | 2.29 |
437.86 | 2.03 | 2.03 |
375.82 | 2.43 | 2.43 |
492.46 | 2.54 | 2.54 |