Basic Information
ID: ALA5054261
Type: Functional
Description: Antitumor activity against human ibrutinib-resistant BTK[C481S] knock-in OCILY10 cells in SCID mouse assessed as tumor growth inhibition at 60 mg/kg, po bid measured after 63 days
Organism: Homo sapiens
Cell type: OCI-Ly10
Activity Charts
Bioactivity
Activity Types for Assay ALA5054261
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.65 | 4.51 | 4.51 |