Assay Report Card

Basic Information

ID: ALA5054291

Type: Binding

Description: Binding affinity to C-terminal His-tagged human BCL-2 (1 to 211 residues) expressed in Escherichia coli/recombinant human VHL (54 to end residues) fused to human N-terminal GST-tagged elongin-C/elongin -B/N-terminal His-tagged CUL2/Rbx1 expressed in baculovirus infected Sf21 insect cells assessed as ternary complex formation at up to 100000 nM measured after 30 mins by AlphaLISA assay

Organism: Homo sapiens

Cell type: Sf21

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1600.47
1600.47