Basic Information
ID: ALA5055692
Type: Binding
Description: Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5055692
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.53 | 3.99 | 3.99 |
| 462.59 | 3.98 | 3.98 |
| 447.57 | 4.52 | 4.52 |
| 476.61 | 4.37 | 4.37 |
| 492.61 | 3.61 | 3.61 |
| 508.62 | 4.49 | 4.49 |
| 544.57 | 4.58 | 4.58 |
| 543.49 | 5.55 | 5.55 |
| 543.44 | 4.63 | 4.63 |
| 495.02 | 4.34 | 4.34 |
| 460.57 | 3.68 | 3.68 |
| 557.52 | 5.73 | 5.73 |
| 529.46 | 4.99 | 4.99 |
| 463.57 | 3.76 | 3.76 |
| 432.52 | 2.90 | 2.90 |
| 536.67 | 5.27 | 5.27 |
| 543.49 | 5.55 | 5.55 |