Basic Information
ID: ALA5055737
Type: Functional
Description: Antagonist activity at mouse Neuropeptide S receptor expressed in HEK293 cells assessed as inhibition of NPS stimulated calcium mobilization at 10 mM treated for 24 mins prior to NPS addition measured immediately by Fluo-4AM dye based FLIPR assay
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5055737
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.49 | 4.12 | 4.12 |
| 481.47 | 4.39 | 4.39 |
| 426.52 | 3.79 | 3.79 |
| 521.59 | 5.86 | 5.86 |
| 459.52 | 4.50 | 4.50 |
| 535.62 | 5.73 | 5.73 |
| 443.57 | 4.14 | 4.14 |
| 361.42 | 2.87 | 2.87 |
| 514.38 | 5.42 | 5.42 |
| 473.55 | 4.73 | 4.73 |
| 487.58 | 5.14 | 5.14 |
| 473.55 | 4.73 | 4.73 |
| 459.52 | 3.52 | 3.52 |
| 501.60 | 5.53 | 5.53 |
| 444.51 | 3.93 | 3.93 |