Basic Information
ID: ALA5055740
Type: Functional
Description: Potency index, ratio of SHA-68 pKb to test compound pKb for antagonist activity at mouse Neuropeptide S receptor expressed in HEK293 cells assessed as inhibition of NPS stimulated calcium mobilization at 10 mM treated for 24 mins prior to NPS addition measured immediately by Fluo-4AM dye based FLIPR assay
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5055740
Ratio pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.47 | 4.39 | 4.39 |
| 521.59 | 5.86 | 5.86 |
| 459.52 | 4.50 | 4.50 |
| 535.62 | 5.73 | 5.73 |
| 361.42 | 2.87 | 2.87 |
| 487.58 | 5.14 | 5.14 |