Basic Information
ID: ALA5055814
Type: Binding
Description: Antagonist activity at rat P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by FLIPR analysis
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5055814
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.16 | 3.09 | 3.09 |
| 339.71 | 3.46 | 3.46 |
| 474.57 | 3.82 | 3.82 |
| 399.80 | 3.61 | 3.61 |
| 334.73 | 2.60 | 2.60 |
| 315.38 | 3.83 | 3.83 |
| 480.95 | 0.87 | 0.87 |
| 488.66 | 4.33 | 4.33 |
| 419.01 | 4.19 | 4.19 |
| 356.73 | 3.55 | 3.55 |
| 832.06 | 9.31 | 9.31 |
| 497.93 | 4.08 | 4.08 |
| 497.93 | 4.08 | 4.08 |
| 314.43 | 3.33 | 3.33 |