Assay Report Card

Basic Information

ID: ALA5055989

Type: Binding

Description: Antagonist activity at rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method

Organism: Rattus norvegicus

Cell type: Oocyte

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1423.61
1295.48
1352.53
1580.78
1369.64
1509.70
1355.61