Basic Information
ID: ALA5055990
Type: Binding
Description: Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Oocyte
Target: Neuronal acetylcholine receptor; alpha3/beta2(ALA1907587)
Document: ALA5055626
Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5055990
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1720.97 | ||
| 2325.64 | ||
| 1423.61 | ||
| 2594.99 | ||
| 1295.48 | ||
| 1352.53 | ||
| 1580.78 | ||
| 1369.64 | ||
| 1509.70 | ||
| 1788.93 |