Basic Information
ID: ALA5057651
Type: Functional
Description: Agonist activity at C5aR1 in human MDM cells assessed as induction of induction of phosphorylation of ERK1/2 at Thr202/Tyr204 residues by measuring efficacy at 4 uM pretreated with antagonist PMX53 for 30 mins followed by compound treatment for 10 mins by AlphaLISA assay relative to control
Organism: Homo sapiens
Cell type: MDM
Activity Charts
Bioactivity
Activity Types for Assay ALA5057651
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 873.07 | -1.96 | -1.96 |
| 941.19 | -0.45 | -0.45 |