Basic Information
ID: ALA5057854
Type: Binding
Description: Non-competitive antagonist activity at human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes decrease in acetylcholine-induced maximum current with non-significant change in Ach potency at IC50 pretreated for 30 secs followed by co-application with acetylcholine measured at holding potential of -60 mV by two-electrode voltage-clamp method
Organism: Homo sapiens
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA5057854
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 682.81 | 2.04 | 2.04 |
| 433.55 | 4.54 | 4.54 |
| 433.55 | 4.54 | 4.54 |
| 433.55 | 4.54 | 4.54 |