Basic Information
ID: ALA5057865
Type: Binding
Description: Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme complex for 45 mins followed by substrates addition and further incubated for 90 mins in presence of ATP at Km concentration by spectrophotometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5057865
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.91 | 5.36 | 5.36 |
| 292.39 | 3.90 | 3.90 |
| 332.41 | 5.08 | 5.08 |
| 430.51 | 3.08 | 3.08 |
| 280.33 | 3.69 | 3.69 |
| 298.39 | 5.57 | 5.57 |
| 299.38 | 4.96 | 4.96 |
| 320.44 | 4.68 | 4.68 |
| 318.38 | 4.51 | 4.51 |
| 322.41 | 3.26 | 3.26 |
| 493.61 | 6.40 | 6.40 |
| 455.56 | 3.58 | 3.58 |
| 346.43 | 5.15 | 5.15 |
| 279.34 | 3.26 | 3.26 |
| 398.51 | 4.65 | 4.65 |
| 223.28 | 3.30 | 3.30 |
| 304.35 | 4.26 | 4.26 |
| 332.41 | 4.90 | 4.90 |
| 431.50 | 3.68 | 3.68 |
| 493.61 | 6.40 | 6.40 |
| 429.52 | 5.10 | 5.10 |
| 507.64 | 6.96 | 6.96 |
| 360.46 | 5.71 | 5.71 |
| 334.45 | 4.98 | 4.98 |
| 442.56 | 4.09 | 4.09 |
| 222.29 | 3.90 | 3.90 |
| 322.41 | 3.26 | 3.26 |
| 412.54 | 4.73 | 4.73 |