Basic Information
ID: ALA5057987
Type: Binding
Description: Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation measured after 48 hrs by spectrophotometry
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA5057987
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 502.31 | 3.17 | 3.17 |
| 517.32 | 3.60 | 3.60 |
| 455.25 | 1.46 | 1.46 |
| 483.30 | 2.24 | 2.24 |
| 451.26 | 2.80 | 2.80 |
| 511.36 | 3.18 | 3.18 |
| 483.30 | 2.54 | 2.54 |
| 467.30 | 3.22 | 3.22 |
| 455.25 | 1.98 | 1.98 |
| 501.32 | 3.90 | 3.90 |
| 513.33 | 2.17 | 2.17 |
| 469.28 | 2.15 | 2.15 |
| 467.30 | 3.27 | 3.27 |
| 499.30 | 1.99 | 1.99 |
| 487.29 | 3.59 | 3.59 |
| 509.34 | 3.07 | 3.07 |
| 469.28 | 2.37 | 2.37 |
| 485.27 | 1.43 | 1.43 |
| 455.25 | 2.07 | 2.07 |
| 441.22 | 1.41 | 1.41 |
| 503.29 | 3.30 | 3.30 |
| 469.28 | 1.85 | 1.85 |
| 440.50 | 4.48 | 4.48 |