Assay Report Card

Basic Information

ID: ALA5057988

Type: Binding

Description: Inhibition of IDO1/IDO2 in IFNgamma/LPS-stimulated human PBMCs assessed as reduction in kynurenine formation at 0.0001 to 10 uM pretreated with compound for 15 mins followed by IFNgamma/LPS stimulation by LC-MS/MS analysis

Organism: Homo sapiens

Cell type: PBMC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
455.251.981.98
485.271.431.43