Basic Information
ID: ALA5096340
Type: Binding
Description: Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and TAMRA labeled Bim BH3 peptide interaction using TAMRA-GWIAQELRRIGDEF as substrate and measured after 120 mins by FP assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5096340
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.90 | 4.92 | 4.92 |
| 406.31 | 5.47 | 5.47 |
| 380.27 | 5.29 | 5.29 |
| 545.49 | 5.99 | 5.99 |
| 519.06 | 4.07 | 4.07 |