Basic Information
ID: ALA5096341
Type: Binding
Description: Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and biotinylated Bim BH3 peptide interaction using Biotin-DMRPEIWIAQELRRIGDEFNAYYARR as substrate incubated for 60 mins by TR-FRET analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5096341
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 613.22 | 5.90 | 5.90 |
| 587.18 | 5.22 | 5.22 |
| 585.17 | 5.00 | 5.00 |
| 599.19 | 5.24 | 5.24 |
| 599.19 | 5.39 | 5.39 |
| 765.46 | 6.44 | 6.44 |
| 712.35 | 5.60 | 5.60 |
| 684.30 | 5.09 | 5.09 |
| 657.23 | 5.35 | 5.35 |
| 714.37 | 6.03 | 6.03 |
| 698.33 | 5.75 | 5.75 |
| 571.14 | 4.61 | 4.61 |