Assay Report Card

Basic Information

ID: ALA5097252

Type: Functional

Description: Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulation by measuring maximal efficacy in presence of IBMX relative to GLP-1(9-36)

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
480.407.087.08
480.407.087.08
480.447.447.44
411.135.995.99
400.105.725.72