Basic Information
ID: ALA5097442
Type: Binding
Description: Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assessed as inhibition constant measured after 120 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Cell membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5097442
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.38 | 2.57 | 2.57 |
| 358.42 | 2.27 | 2.27 |
| 419.38 | 3.45 | 3.45 |
| 369.38 | 2.57 | 2.57 |
| 345.38 | 1.41 | 1.41 |
| 351.39 | 2.43 | 2.43 |
| 344.39 | 2.02 | 2.02 |
| 381.41 | 2.44 | 2.44 |
| 381.41 | 2.44 | 2.44 |
| 345.38 | 1.41 | 1.41 |
| 358.42 | 2.27 | 2.27 |
| 350.40 | 3.04 | 3.04 |
| 350.40 | 3.04 | 3.04 |
| 428.84 | 3.55 | 3.55 |
| 351.39 | 2.43 | 2.43 |
| 371.46 | 2.18 | 2.18 |
| 351.39 | 2.43 | 2.43 |
| 358.42 | 2.27 | 2.27 |
| 409.32 | 3.43 | 3.43 |
| 369.38 | 2.57 | 2.57 |
| 351.39 | 2.43 | 2.43 |
| 354.39 | 1.77 | 1.77 |
| 381.41 | 2.44 | 2.44 |
| 350.40 | 3.04 | 3.04 |
| 344.39 | 2.02 | 2.02 |
| 350.40 | 3.04 | 3.04 |
| 394.40 | 2.90 | 2.90 |
| 352.37 | 1.83 | 1.83 |
| 390.43 | 2.80 | 2.80 |
| 378.84 | 2.67 | 2.67 |