Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assesse...

Basic Information

ID: ALA5097442

Type: Binding

Description: Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assessed as inhibition constant measured after 120 mins by liquid scintillation counting analysis

Format: BAO_0000249

Organism: Homo sapiens

Cell type: HEK293

Subcellular Fraction: Cell membrane

Target: Sigma intracellular receptor 2(ALA4105907)

Document: ALA5096172

Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assessed as inhibition constant measured after 120 mins by liquid scintillation counting analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5097442

Total(32)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
369.38	2.57	2.57
358.42	2.27	2.27
419.38	3.45	3.45
369.38	2.57	2.57
345.38	1.41	1.41
351.39	2.43	2.43
344.39	2.02	2.02
381.41	2.44	2.44
381.41	2.44	2.44
345.38	1.41	1.41
358.42	2.27	2.27
350.40	3.04	3.04
350.40	3.04	3.04
428.84	3.55	3.55
351.39	2.43	2.43
371.46	2.18	2.18
351.39	2.43	2.43
358.42	2.27	2.27
409.32	3.43	3.43
369.38	2.57	2.57
351.39	2.43	2.43
354.39	1.77	1.77
381.41	2.44	2.44
350.40	3.04	3.04
344.39	2.02	2.02
350.40	3.04	3.04
394.40	2.90	2.90
352.37	1.83	1.83
390.43	2.80	2.80
378.84	2.67	2.67