Basic Information
ID: ALA5097985
Type: Binding
Description: Inhibition of full length N-terminal GST-tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Baculovirus infected Sf9 cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5097985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.42 | 3.34 | 3.34 |
| 355.42 | 4.07 | 4.07 |
| 588.69 | 5.79 | 5.79 |
| 602.71 | 6.18 | 6.18 |
| 574.66 | 5.40 | 5.40 |
| 546.61 | 4.62 | 4.62 |
| 483.50 | 3.07 | 3.07 |
| 515.59 | 5.30 | 5.30 |
| 558.62 | 4.78 | 4.78 |
| 589.71 | 6.62 | 6.62 |
| 513.57 | 4.07 | 4.07 |
| 440.48 | 3.59 | 3.59 |
| 527.60 | 4.46 | 4.46 |
| 608.68 | 6.15 | 6.15 |
| 518.60 | 4.70 | 4.70 |
| 532.62 | 5.09 | 5.09 |
| 472.52 | 3.73 | 3.73 |
| 520.56 | 4.76 | 4.76 |
| 616.74 | 6.57 | 6.57 |
| 499.55 | 3.68 | 3.68 |
| 485.52 | 3.29 | 3.29 |
| 541.63 | 5.42 | 5.42 |
| 546.60 | 5.16 | 5.16 |