Basic Information
ID: ALA5098052
Type: Binding
Description: Inhibition of recombinant His-tagged HIV-1 NL4-3 integrase expressed in Escherichia coli BL21 pLys using GTGTGGAAAATCTCTAGCA/ACTGCTAGAGATTTTCCACAC as DNA substrate incubated for 2 hrs by densitometric analysis
Organism: Human immunodeficiency virus 1
Strain: NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA5098052
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.42 | 0.91 | 0.91 |
| 453.47 | 5.62 | 5.62 |
| 427.43 | 4.78 | 4.78 |
| 500.35 | 6.25 | 6.25 |
| 447.42 | 4.19 | 4.19 |
| 495.51 | 6.26 | 6.26 |
| 403.41 | 4.47 | 4.47 |
| 500.35 | 6.25 | 6.25 |
| 367.38 | 3.57 | 3.57 |
| 472.30 | 5.77 | 5.77 |
| 479.51 | 6.13 | 6.13 |
| 472.30 | 5.77 | 5.77 |
| 339.32 | 3.09 | 3.09 |
| 343.81 | 3.89 | 3.89 |