Basic Information
ID: ALA5098265
Type: Binding
Description: Protac activity at CRBN/EML4-ALK in human NCI-H3122 cells assessed as induction of EML4-ALK fusion protein degradation at 1 uM incubated for 16 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: NCI-H3122
Activity Charts
Bioactivity
Activity Types for Assay ALA5098265
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 794.91 | 4.10 | 4.10 |
| 711.78 | 3.63 | 3.63 |
| 866.04 | 4.47 | 4.47 |
| 810.96 | 4.78 | 4.78 |
| 654.73 | 4.20 | 4.20 |
| 754.85 | 3.22 | 3.22 |
| 894.09 | 5.25 | 5.25 |
| 837.98 | 3.69 | 3.69 |
| 737.86 | 4.66 | 4.66 |
| 782.90 | 4.00 | 4.00 |