Basic Information
ID: ALA5098269
Type: Binding
Description: Protac activity at CRBN/NPM-ALK in human KARPAS-299 cells assessed as induction of NPM-ALK fusion protein degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: KARPAS-299
Activity Charts
Bioactivity
Activity Types for Assay ALA5098269
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 767.89 | 5.19 | 5.19 |
| 794.91 | 4.10 | 4.10 |
| 711.78 | 3.63 | 3.63 |
| 739.83 | 4.41 | 4.41 |
| 810.96 | 4.78 | 4.78 |
| 654.73 | 4.20 | 4.20 |
| 754.85 | 3.22 | 3.22 |
| 782.90 | 4.00 | 4.00 |