Basic Information
ID: ALA5098418
Type: Binding
Description: Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-MRM analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5098418
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.39 | -2.24 | -2.24 |
| 528.57 | -1.14 | -1.14 |
| 524.54 | -1.72 | -1.72 |
| 507.55 | 0.49 | 0.49 |
| 492.54 | 0.18 | 0.18 |
| 522.57 | 0.11 | 0.11 |
| 526.55 | -1.06 | -1.06 |
| 496.53 | -0.19 | -0.19 |
| 528.53 | -0.25 | -0.25 |
| 524.54 | -1.72 | -1.72 |
| 506.52 | -0.94 | -0.94 |
| 449.52 | 1.32 | 1.32 |
| 497.56 | 0.15 | 0.15 |
| 483.53 | -0.15 | -0.15 |
| 526.55 | -1.06 | -1.06 |
| 513.56 | -0.15 | -0.15 |
| 501.52 | -0.02 | -0.02 |
| 507.55 | 1.17 | 1.17 |
| 510.56 | -0.36 | -0.36 |
| 533.59 | 1.00 | 1.00 |
| 259.31 | 0.96 | 0.96 |
| 501.52 | -0.02 | -0.02 |
| 273.34 | 1.31 | 1.31 |
| 513.58 | 0.55 | 0.55 |
| 507.55 | 0.49 | 0.49 |
| 517.97 | 0.50 | 0.50 |
| 513.56 | -0.15 | -0.15 |
| 407.43 | 0.20 | 0.20 |
| 506.57 | 0.57 | 0.57 |
| 501.52 | -0.02 | -0.02 |
| 508.54 | -0.12 | -0.12 |
| 533.59 | 1.00 | 1.00 |
| 497.56 | 0.15 | 0.15 |
| 508.54 | -0.28 | -0.28 |
| 533.59 | 1.00 | 1.00 |
| 513.56 | -0.15 | -0.15 |
| 528.53 | -0.25 | -0.25 |
| 528.53 | -0.25 | -0.25 |
| 482.50 | -0.80 | -0.80 |
| 507.56 | -0.88 | -0.88 |
| 464.53 | 0.26 | 0.26 |
| 493.52 | 0.78 | 0.78 |
| 496.53 | -0.19 | -0.19 |
| 562.43 | 0.61 | 0.61 |
| 508.54 | -0.12 | -0.12 |
| 562.43 | 0.61 | 0.61 |
| 513.58 | 0.55 | 0.55 |
| 508.54 | -0.28 | -0.28 |
| 421.46 | 0.54 | 0.54 |
| 521.58 | 0.53 | 0.53 |
| 508.54 | -0.12 | -0.12 |
| 497.56 | 0.15 | 0.15 |
| 517.97 | 0.50 | 0.50 |
| 508.54 | -0.28 | -0.28 |
| 522.52 | -0.76 | -0.76 |
| 506.52 | -0.94 | -0.94 |
| 514.55 | 0.80 | 0.80 |
| 517.97 | 0.50 | 0.50 |
| 507.55 | -0.17 | -0.17 |
| 562.43 | 0.61 | 0.61 |