Basic Information
ID: ALA5098595
Type: Binding
Description: Inhibition of human SHP2 assessed as downregulation of PERK level in human KYSE520 cells incubated for 2 hrs by Alpha screen assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: KYSE520
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA5096203
Inhibition of human SHP2 assessed as downregulation of PERK level in human KYSE520 cells incubated for 2 hrs by Alpha screen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5098595
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.34 | 3.66 | 3.66 |
| 372.86 | 2.43 | 2.43 |
| 367.28 | 3.17 | 3.17 |
| 487.01 | 2.72 | 2.72 |
| 393.28 | 2.94 | 2.94 |
| 463.37 | 3.15 | 3.15 |
| 442.96 | 2.83 | 2.83 |
| 453.37 | 2.67 | 2.67 |
| 457.79 | 3.83 | 3.83 |
| 419.32 | 3.27 | 3.27 |
| 377.28 | 3.64 | 3.64 |
| 417.34 | 4.42 | 4.42 |
| 423.34 | 3.18 | 3.18 |
| 491.34 | 4.20 | 4.20 |
| 448.35 | 3.05 | 3.05 |
| 466.37 | 2.28 | 2.28 |