Basic Information
ID: ALA5098675
Type: Binding
Description: Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA polymerase II phosphorylation at ser2 residue incubated for 6 hrs by fluorescence based assay
Organism: Homo sapiens
Cell type: MCF7
Activity Charts
Bioactivity
Activity Types for Assay ALA5098675
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.39 | 3.84 | 3.84 |
| 339.41 | 4.19 | 4.19 |
| 433.56 | 3.38 | 3.38 |
| 417.48 | 4.88 | 4.88 |
| 404.51 | 3.94 | 3.94 |
| 437.54 | 2.31 | 2.31 |
| 497.60 | 4.37 | 4.37 |
| 367.42 | 4.10 | 4.10 |
| 423.52 | 2.20 | 2.20 |
| 407.52 | 2.68 | 2.68 |
| 407.52 | 2.90 | 2.90 |
| 422.53 | 2.64 | 2.64 |
| 369.44 | 3.55 | 3.55 |
| 378.48 | 3.70 | 3.70 |
| 458.61 | 4.74 | 4.74 |
| 326.37 | 4.27 | 4.27 |
| 336.44 | 3.44 | 3.44 |
| 432.59 | 5.41 | 5.41 |
| 448.57 | 3.65 | 3.65 |
| 463.58 | 3.01 | 3.01 |
| 410.49 | 3.65 | 3.65 |
| 461.61 | 4.16 | 4.16 |
| 421.55 | 3.24 | 3.24 |
| 453.61 | 3.02 | 3.02 |
| 491.64 | 3.48 | 3.48 |
| 405.50 | 4.37 | 4.37 |
| 400.47 | 4.42 | 4.42 |
| 435.57 | 3.32 | 3.32 |
| 422.53 | 2.64 | 2.64 |
| 477.61 | 3.09 | 3.09 |
| 446.55 | 4.20 | 4.20 |
| 393.49 | 2.20 | 2.20 |
| 447.58 | 3.77 | 3.77 |
| 381.45 | 4.54 | 4.54 |