Basic Information
ID: ALA5099705
Type: Binding
Description: Inhibition of human DGAT2 expressed in Sf9 insect cell membrane using [1-14C]decanoyl-CoA and 1,2-didecanoyl-sn-glycerol as substrates assessed as incorporation of [1-14C]decanoyl into triacylglycerol preincubated for 120 mins followed by substrate addition and measured after 40 mins by scintillation counting method
Organism: Homo sapiens
Cell type: Sf9
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5099705
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.43 | 2.64 | 2.64 |
| 421.46 | 3.03 | 3.03 |
| 437.46 | 2.01 | 2.01 |
| 434.46 | 2.09 | 2.09 |
| 365.39 | 2.87 | 2.87 |
| 421.46 | 3.03 | 3.03 |
| 409.45 | 2.63 | 2.63 |
| 455.50 | 2.04 | 2.04 |
| 471.54 | 2.68 | 2.68 |
| 414.51 | 2.42 | 2.42 |
| 407.43 | 2.64 | 2.64 |
| 415.49 | 1.82 | 1.82 |