Basic Information
ID: ALA5099717
Type: ADME
Description: Reversible inhibition of CYP2C8 in pooled human liver microsomes using desethylamodiaquine as substrate incubated for 10 mins in presence of NADPH by HPLC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5099717
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.43 | 2.64 | 2.64 |
| 409.45 | 2.63 | 2.63 |