ID: ALA5099719
Type: ADME
Description: Reversible inhibition of CYP2C19 in pooled human liver microsomes using 4-Hydroxymephenytoin as substrate incubated for 20 mins in presence of NADPH by HPLC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Bioactivity
Activity Types for Assay ALA5099719
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
407.43 | 2.64 | 2.64 |
409.45 | 2.63 | 2.63 |