Activation of NF-kappaB transcriptional activity in mouse RAW-Blue cells expressing NOD2 and TLR7 at 1 uM preincubated with TLR7 antagonist, M5049 for...

Basic Information

ID: ALA5099920

Type: Binding

Description: Activation of NF-kappaB transcriptional activity in mouse RAW-Blue cells expressing NOD2 and TLR7 at 1 uM preincubated with TLR7 antagonist, M5049 for 1 hr followed by compound addition and measured after 18 hrs by quanti-blue/SEAP-based spectrophotometry analysis

Format: BAO_0000219

Organism: Mus musculus

Cell type: RAW-Blue

Target:  Unchecked(ALA612545)

Document:  ALA5096231

Activation of NF-kappaB transcriptional activity in mouse RAW-Blue cells expressing NOD2 and TLR7 at 1 uM preincubated with TLR7 antagonist, M5049 for 1 hr followed by compound addition and measured after 18 hrs by quanti-blue/SEAP-based spectrophotometry analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
988.113.913.91
933.031.721.72