Basic Information
ID: ALA5100170
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells to IC50 for inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5100170
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 421.50 | 4.55 | 4.55 |
| 335.41 | 2.80 | 2.80 |
| 314.34 | 1.37 | 1.37 |
| 460.53 | 2.83 | 2.83 |
| 437.54 | 3.51 | 3.51 |
| 443.52 | 3.63 | 3.63 |
| 455.53 | 3.65 | 3.65 |
| 457.50 | 3.04 | 3.04 |
| 445.47 | 3.18 | 3.18 |
| 397.48 | 2.67 | 2.67 |
| 478.52 | 2.97 | 2.97 |
| 495.47 | 4.05 | 4.05 |
| 415.47 | 2.81 | 2.81 |
| 413.47 | 2.37 | 2.37 |
| 419.43 | 2.64 | 2.64 |
| 463.51 | 3.52 | 3.52 |
| 441.50 | 3.34 | 3.34 |
| 429.49 | 3.12 | 3.12 |
| 435.88 | 3.16 | 3.16 |
| 470.55 | 3.10 | 3.10 |
| 431.46 | 2.51 | 2.51 |
| 469.44 | 3.52 | 3.52 |
| 444.51 | 2.57 | 2.57 |